Co-codamol and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Co-codamol (acetaminophen; codeine phosphate) and Clexane (enoxaparin sodium). Common drug interactions include infection among females and pulmonary embolism among males.

The phase IV clinical study analyzes what interactions people have when they take Co-codamol and Clexane. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Co-codamol?

Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.



On Jul, 06, 2026

27 people who take Co-codamol and Clexane together, and have interactions are studied.

Co-codamol and Clexane drug interactions.

What are the common drug interactions of Co-Codamol and Clexane, by gender? *:

female:

  1. Infection
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  7. Nausea (feeling of having an urge to vomit)
  8. Vomiting
  9. Crying
  10. Eating disorder

male:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Cardiac arrest
  3. Drug ineffective
  4. Epistaxis (bleed from the nose)
  5. Respiratory depression (respiration has a rate below 12 breaths)
  6. Death
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Arthralgia (joint pain)
  9. Cellulitis (infection under the skin)
  10. Femoral neck fracture (neck of femur bone fracture)

What are the common drug interactions of Co-Codamol and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Gun shot wound
  2. Lethargy (tiredness)
  3. Lower respiratory tract infection
  4. Nausea (feeling of having an urge to vomit)
  5. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)
  8. Vomiting

30-39:

n/a

40-49:

n/a

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Infection
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  5. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  6. Crying
  7. Eating disorder
  8. Nausea (feeling of having an urge to vomit)
  9. Pyrexia (fever)

60+:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Cardiac arrest
  3. Infection
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Arthralgia (joint pain)
  6. Cellulitis (infection under the skin)
  7. Infusion related reaction
  8. Vomiting
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 22.22%
  2. Constipation: 5 people, 18.52%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 14.81%
  4. Sedation: 4 people, 14.81%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 14.81%
  6. Mouth Ulcers: 4 people, 14.81%
  7. Infection: 3 people, 11.11%
  8. Anaemia (lack of blood): 3 people, 11.11%
  9. Blood Glucose Increased: 3 people, 11.11%
  10. Blood Potassium Decreased: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Co-codamol and Clexane?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Co-codamol and Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Co-codamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Co-codamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clexane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and enoxaparin sodium (the active ingredients of Co-codamol and Clexane, respectively), and Co-codamol and Clexane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: