Co-codamol and Temaz drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Co-codamol (acetaminophen; codeine phosphate) and Temaz (temazepam). Common drug interactions include haemoglobin decreased among females and metabolic acidosis among males.
The phase IV clinical study analyzes what interactions people have when they take Co-codamol and Temaz. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.
What is Co-codamol?
Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.
What is Temaz?
Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.
53 people who take Co-codamol and Temaz together, and have interactions are studied.

What are the common drug interactions of Co-Codamol and Temaz, by gender? *:
female:
- Haemoglobin decreased
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Renal mass (mass in kidney)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Urinary tract infection
- Abortion spontaneous (naturally occurring miscarriage)
- Cardiac failure congestive
- Chest discomfort
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Epistaxis (bleed from the nose)
male:
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Hypotension (abnormally low blood pressure)
- Fall
- Fatigue (feeling of tiredness)
- Hypokalaemia (low potassium)
- Multiple drug overdose
- Muscular weakness (muscle weakness)
- Renal failure (kidney dysfunction)
- Blood creatinine increased
- Multiple drug overdose intentional
What are the common drug interactions of Co-Codamol and Temaz, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Rash
- Erythema (redness of the skin)
- Loss of consciousness
- Pancreatitis acute (sudden inflammation of pancreas)
10-19:
n/a
20-29:
n/a
30-39:
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Hypotension (abnormally low blood pressure)
- Hypoxia (low oxygen in tissues)
- Loss of consciousness
- Crystalluria (crystals found in the urine)
- Suicide attempt
- Heart rate increased
- Overdose
- Hypokalaemia (low potassium)
- Multiple drug overdose
40-49:
- Alcohol poisoning
- Face oedema (swelling of face)
- Intentional self-injury
- Oedema peripheral (superficial swelling)
- Overdose
- Poisoning deliberate
- Suicidal ideation
50-59:
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Hallucination (an experience involving the perception of something not present)
60+:
- Dizziness
- Fall
- Renal failure acute (rapid kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Blood pressure decreased
- Chills (felling of cold)
- Dyspnoea (difficult or laboured respiration)
- Haemoglobin decreased
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Staphylococcal bacteraemia (a bacterial infection of blood)
What are the existing conditions these people have? *
- Urinary Tract Infection: 5 people, 9.43%
- High Blood Pressure: 5 people, 9.43%
- Stomatitis (inflammation of mucous membrane of mouth): 4 people, 7.55%
- Depression: 4 people, 7.55%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.66%
- Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 3 people, 5.66%
- Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.66%
* Approximation only. Some reports may have incomplete information.
Do you take Co-codamol and Temaz?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Co-codamol (2,364 reports)
- Temaz (42,293 reports)
Browse all drug interactions of Co-codamol and Temaz:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Co-codamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Temaz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Co-codamol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Temaz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and temazepam (the active ingredients of Co-codamol and Temaz, respectively), and Co-codamol and Temaz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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