Cobalamin and Meropenem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cobalamin (vitamin b12) and Meropenem (meropenem). Common drug interactions include pneumonia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cobalamin and Meropenem. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Cobalamin?

Cobalamin has active ingredients of vitamin b12. eHealthMe is studying from 3,429 Cobalamin users. Check the latest studies of Cobalamin.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 29, 2026

44 people who take Cobalamin and Meropenem together, and have interactions are studied.

Cobalamin and Meropenem drug interactions.

What are the common drug interactions of Cobalamin and Meropenem, by gender? *:

female:

  1. Pneumonia
  2. Diarrhoea
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  5. Vomiting
  6. Nausea (feeling of having an urge to vomit)
  7. Overdose
  8. Platelet count decreased
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Brain abscess

male:

  1. Pneumonia
  2. Septic shock (shock due to blood infection)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Decreased appetite
  5. Electrocardiogram qt prolonged
  6. Generalised oedema (swelling all over the body)
  7. Headache (pain in head)
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. Nausea (feeling of having an urge to vomit)
  10. Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Cobalamin and Meropenem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Electrocardiogram qt prolonged
  2. Haemoglobin decreased
  3. Neuropathy peripheral (surface nerve damage)
  4. Relapsing fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea)

40-49:

  1. Brain abscess
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Haematochezia (passage of stools containing blood)
  4. Mastication disorder (disease of chewing food)
  5. Melaena (the passage of black, tarry stools)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Otorrhoea (discharge from the ear)
  8. Subcutaneous abscess
  9. Arthralgia (joint pain)
  10. Cardiomegaly (increased size of heart than normal)

50-59:

  1. Constipation
  2. Cough
  3. Death
  4. Diarrhoea
  5. Fatigue (feeling of tiredness)
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Hypokalaemia (low potassium)
  9. Infection
  10. Lymphoma (cancer that begins in immune system cells)

60+:

  1. Pneumonia
  2. Diarrhoea
  3. Anaemia (lack of blood)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac failure
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Decreased appetite
  9. Generalised oedema (swelling all over the body)
  10. Headache (pain in head)

What are the existing conditions these people have? *

  1. Constipation: 10 people, 22.73%
  2. Multiple Myeloma (cancer of the plasma cells): 10 people, 22.73%
  3. Fever: 8 people, 18.18%
  4. High Blood Pressure: 8 people, 18.18%
  5. Neuralgia (pain in one or more nerves): 7 people, 15.91%
  6. Diabetes: 6 people, 13.64%
  7. Pain: 6 people, 13.64%
  8. Neuropathy Peripheral (surface nerve damage): 6 people, 13.64%
  9. Insomnia (sleeplessness): 6 people, 13.64%
  10. Local Anaesthesia: 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

Do you take Cobalamin and Meropenem?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cobalamin and Meropenem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Meropenem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cobalamin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Meropenem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on vitamin b12 and meropenem (the active ingredients of Cobalamin and Meropenem, respectively), and Cobalamin and Meropenem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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