Codeine sulfate and Modafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine sulfate (codeine sulfate) and Modafinil (modafinil). Common drug interactions include anxiety among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine sulfate and Modafinil. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

14 people who take Codeine sulfate and Modafinil together, and have interactions are studied.

Codeine sulfate and Modafinil drug interactions.

What are the common drug interactions of Codeine Sulfate and Modafinil, by gender? *:

female:

Anxiety
Asthma
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Hunger
Hypersensitivity
Memory impairment
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)

male:

Asthenia (weakness)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Pneumonia
Leukaemia (blood or bone marrow cancer)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cough
Fatigue (feeling of tiredness)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Codeine Sulfate and Modafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Suicidal ideation
Drug ineffective
Hypersensitivity
Memory impairment
Nephrolithiasis (calculi in the kidneys)

40-49:

n/a

50-59:

Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)

60+:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cough
Dysphagia (a condition in which swallowing is difficult or painful)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 64.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%
Thyroid Diseases: 1 person, 7.14%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
Ill-Defined Disorder: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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