Codeine sulfate and Vioxx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine sulfate (codeine sulfate) and Vioxx (rofecoxib). Common drug interactions include dermatitis among females and apathy among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine sulfate and Vioxx. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

On Aug, 04, 2026

38 people who take Codeine sulfate and Vioxx together, and have interactions are studied.

Codeine sulfate and Vioxx drug interactions.

What are the common drug interactions of Codeine Sulfate and Vioxx, by gender? *:

female:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Face oedema (swelling of face)
Gingival swelling (gums swelling)
Hyperplasia (enlargement of an organ or tissue)
Hypoaesthesia (reduced sense of touch or sensation)
Inflammation
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)

male:

Apathy
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Eye pain
Fatigue (feeling of tiredness)
Folliculitis (infection of hair root)
Haemorrhage (bleeding)
Herpes zoster
Hyperglycaemia (high blood sugar)

What are the common drug interactions of Codeine Sulfate and Vioxx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Insomnia (sleeplessness)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Apathy
Arthralgia (joint pain)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Depression

50-59:

Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gait disturbance
General physical health deterioration (weak health status)
Headache (pain in head)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Impaired healing

60+:

Anaphylactic reaction (serious allergic reaction)
Drug intolerance (drug sensitivity)
Dysgeusia (disorder of the sense of taste)
Emotional distress
Face oedema (swelling of face)
Gingival swelling (gums swelling)
Hyperplasia (enlargement of an organ or tissue)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing
Inflammation

What are the existing conditions these people have? *

Adenocarcinoma Pancreas (cancer of pancreas): 16 people, 42.11%
Type 2 Diabetes: 16 people, 42.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 21.05%
Stress And Anxiety: 7 people, 18.42%
Metastases To Bone (cancer spreads to bone): 7 people, 18.42%
Bone Pain: 6 people, 15.79%
Breast Cancer: 6 people, 15.79%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 13.16%
Breast Cancer Metastatic: 3 people, 7.89%
Insomnia (sleeplessness): 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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