Codeine and Belsomra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine (codeine sulfate) and Belsomra (suvorexant). Common drug interactions include headache among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine and Belsomra. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Belsomra?

Belsomra has active ingredients of suvorexant. It is often used in insomnia. eHealthMe is studying from 12,961 Belsomra users. Check the latest studies of Belsomra.

On Jul, 11, 2026

19 people who take Codeine and Belsomra together, and have interactions are studied.

What are the common drug interactions of Codeine and Belsomra, by gender? *:

female:

Headache (pain in head)
Arthralgia (joint pain)
Constipation
Decreased appetite
Diarrhoea
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Pain in extremity
Pain in jaw

male:

Drug ineffective
Memory impairment
Leukocytosis (increased white blood cells)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Mouth haemorrhage (bleeding from mouth)
Oral viral infection
Pharyngeal erythema (pharyngeal redness)
Platelet count decreased
Pneumonia

What are the common drug interactions of Codeine and Belsomra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug abuse

40-49:

Abdominal pain
Appendicitis (inflammation of the appendix)
Cardiac failure
Chronic kidney disease
Decreased appetite
Disease progression
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Faecalith (hard mass of fecal matter)
Febrile neutropenia (fever with reduced white blood cells)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Decreased appetite
Diarrhoea
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Pain in extremity
Pain in jaw
Palpitations (feelings or sensations that your heart is pounding or racing)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Vitreous haemorrhage (intraocular (inside the eye) bleeding)

60+:

Interstitial lung disease
Overdose
Duodenal ulcer
Erythema multiforme (a type of hypersensitivity reaction)
Humerus fracture (injury to the upper arm bone)
Migraine (headache)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the existing conditions these people have? *

Constipation: 6 people, 31.58%
Headache (pain in head): 6 people, 31.58%
Diarrhea: 6 people, 31.58%
Nausea (feeling of having an urge to vomit): 6 people, 31.58%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 26.32%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 26.32%
High Blood Pressure: 5 people, 26.32%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 21.05%
Seasonal Allergy (allergic condition due to certain season): 4 people, 21.05%
Allergic Rhinitis: 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and Belsomra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously