Codeine and Bumex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Codeine (codeine sulfate) and Bumex (bumetanide). Common drug interactions include chronic kidney disease among females.
The phase IV clinical study analyzes what interactions people have when they take Codeine and Bumex. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.
What is Bumex?
Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.
19 people who take Codeine and Bumex together, and have interactions are studied.

What are the common drug interactions of Codeine and Bumex, by gender? *:
female:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anxiety
- Arthralgia (joint pain)
- Asthenia (weakness)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Cataract (clouding of the lens inside the eye)
- Contusion (a type of hematoma of tissue in which capillaries)
- Depression
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
male:
n/a
What are the common drug interactions of Codeine and Bumex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Death
- Hepatic failure (liver failure)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Cataract (clouding of the lens inside the eye)
- Chronic kidney disease
- Essential hypertension (primary hypertension)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hot flush (sudden feelings of heat)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
60+:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gout (uric acid crystals building up in the body)
- Night sweats (sweating in night)
- Renal tubular necrosis (death of kidney tubules)
- Weight decreased
- Renal failure (kidney dysfunction)
- Drug hypersensitivity
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 42.11%
- Stress And Anxiety: 4 people, 21.05%
- Gout (uric acid crystals building up in the body): 3 people, 15.79%
- High Blood Cholesterol: 3 people, 15.79%
- High Blood Pressure: 3 people, 15.79%
- Hypersensitivity: 2 people, 10.53%
- Indigestion: 2 people, 10.53%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.53%
- Cardiac Disorder: 2 people, 10.53%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Codeine and Bumex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Codeine and Bumex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bumex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bumex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on codeine sulfate and bumetanide (the active ingredients of Codeine and Bumex, respectively), and Codeine and Bumex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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