Codeine and Omeprazole magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine (codeine sulfate) and Omeprazole magnesium (omeprazole magnesium). Common drug interactions include restless legs syndrome among females and activated partial thromboplastin time prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine and Omeprazole magnesium. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Omeprazole magnesium?

Omeprazole magnesium has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,956 Omeprazole magnesium users. Check the latest studies of Omeprazole magnesium.

On Jul, 31, 2026

20 people who take Codeine and Omeprazole magnesium together, and have interactions are studied.

Codeine and Omeprazole magnesium drug interactions.

What are the common drug interactions of Codeine and Omeprazole Magnesium, by gender? *:

female:

Restless legs syndrome (a powerful urge to move your legs)
Restlessness (not able to rest)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sensory loss (senses loss)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Skin discolouration (change of skin colour)
Sleep disorder
Speech disorder
Suicidal ideation

male:

Activated partial thromboplastin time prolonged
Blood albumin decreased
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
Costochondritis (chest wall pain)
Drug hypersensitivity
Drug ineffective
Inflammatory pain
Blood alkaline phosphatase increased

What are the common drug interactions of Codeine and Omeprazole Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Incontinence (lack of moderation or self-control)
Malaise (a feeling of general discomfort or uneasiness)
Mania (a state of abnormally elevated or irritable mood)
Menstrual disorder (disease of menstrual cycle)
Mood swings (an extreme or rapid change in mood)
Muscle disorder (muscle disease)

30-39:

Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Loss of consciousness
Necrosis ischaemic (death of cell due to lack of blood supply)
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Septic shock (shock due to blood infection)

40-49:

Drug hypersensitivity
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Contrast media allergy (reaction associated with the use of intravenous contrast material during radiology)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Iodine allergy

50-59:

Blood sodium decreased
Activated partial thromboplastin time prolonged
Blood albumin decreased
Blood alkaline phosphatase increased
Blood fibrinogen increased
C-reactive protein increased
Dyspnoea (difficult or laboured respiration)
Lower respiratory tract infection
Platelet count increased
Pneumonia

60+:

Cough
Dental caries
Rash
Rash pruritic (redness with itching)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Tendonitis (a condition that causes pain and swelling of tendons)
Urinary tract infection
Viral upper respiratory tract infection
Inappropriate antidiuretic hormone secretion

What are the existing conditions these people have? *

Depression: 4 people, 20.00%
Indigestion: 4 people, 20.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 15.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 15.00%
Sleep Disorder: 3 people, 15.00%
High Blood Pressure: 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Infection: 2 people, 10.00%
Inflammation: 2 people, 10.00%
Cough: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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