Codeine and Tryptophan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Codeine (codeine sulfate) and Tryptophan (l - tryptophan). Common drug interactions include asthma among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Codeine and Tryptophan. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.
What is Tryptophan?
Tryptophan has active ingredients of l - tryptophan. eHealthMe is studying from 700 Tryptophan users. Check the latest studies of Tryptophan.
46 people who take Codeine and Tryptophan together, and have interactions are studied.

What are the common drug interactions of Codeine and Tryptophan, by gender? *:
female:
- Asthma
- Hypotension (abnormally low blood pressure)
- Influenza like illness
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pruritus (severe itching of the skin)
- Drug ineffective
- Abdominal pain
- Blood pressure systolic decreased
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Fatigue (feeling of tiredness)
male:
- Drug ineffective
- Hand fracture
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Waldenstrom's macroglobulinaemia (cancer affects small lymphocytes (white blood cells))
- Abdominal pain
- Diarrhoea
- Hip arthroplasty
- Malaise (a feeling of general discomfort or uneasiness)
What are the common drug interactions of Codeine and Tryptophan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abnormal behaviour
- Anxiety
- Asthenia (weakness)
- Cachexia (loss of weight)
- Chest discomfort
- Chest pain
- Chills (felling of cold)
- Confusional state
- Constipation
- Depression
30-39:
n/a
40-49:
n/a
50-59:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pruritus (severe itching of the skin)
- Drug ineffective
- Abdominal pain upper
- Breast abscess
- Cough
- Electrocardiogram qt prolonged
- Fall
- Fatigue (feeling of tiredness)
- Impaired healing
60+:
- Drug ineffective
- Hand fracture
- Hip arthroplasty
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Waldenstrom's macroglobulinaemia (cancer affects small lymphocytes (white blood cells))
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 30.43%
- Pneumonia: 3 people, 6.52%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 6.52%
- Medullary Thyroid Cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland): 3 people, 6.52%
- Depression: 3 people, 6.52%
* Approximation only. Some reports may have incomplete information.
Do you take Codeine and Tryptophan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Codeine (42,342 reports)
- Tryptophan (700 reports)
Browse all drug interactions of Codeine and Tryptophan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tryptophan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tryptophan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on codeine sulfate and l - tryptophan (the active ingredients of Codeine and Tryptophan, respectively), and Codeine and Tryptophan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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