Codeine and Varenicline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine (codeine sulfate) and Varenicline (varenicline). Common drug interactions include balance disorder among females and bankruptcy among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine and Varenicline. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

What is Varenicline?

Varenicline has active ingredients of varenicline. It is often used in quit smoking. eHealthMe is studying from 1,066 Varenicline users. Check the latest studies of Varenicline.

On Jul, 29, 2026

11 people who take Codeine and Varenicline together, and have interactions are studied.

Codeine and Varenicline drug interactions.

What are the common drug interactions of Codeine and Varenicline, by gender? *:

female:

Balance disorder
Dizziness
Dysarthria (speech disorder)
Gait disturbance
Vision blurred

male:

Bankruptcy
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Peripheral swelling
Pruritus (severe itching of the skin)
Pulmonary oedema (fluid accumulation in the lungs)
Rash
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Suicidal ideation
Suicide attempt

What are the common drug interactions of Codeine and Varenicline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bankruptcy
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Compulsive shopping
Dermatillomania (skin picking disorders)
Eating disorder
Erectile dysfunction
Homeless
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)

40-49:

Dizziness
Dysarthria (speech disorder)
Gait disturbance
Vision blurred
Balance disorder

50-59:

n/a

60+:

Haemoglobin decreased
Peripheral swelling
Pruritus (severe itching of the skin)
Pulmonary oedema (fluid accumulation in the lungs)
Rash
Haematocrit decreased
Platelet count decreased
Red blood cell count decreased
White blood cell count decreased

What are the existing conditions these people have? *

Wheezing (a high-pitched whistling sound made while you breath): 2 people, 18.18%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 18.18%
Affective Disorder (mental disorder): 2 people, 18.18%
Agitation (state of anxiety or nervous excitement): 2 people, 18.18%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
Bipolar Disorder (mood disorder): 2 people, 18.18%
Cardiac Disorder: 2 people, 18.18%
Depression: 2 people, 18.18%
Dizziness: 2 people, 18.18%
Drowsiness: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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