Cogentin and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cogentin (benztropine mesylate) and Premarin (estrogens, conjugated). Common drug interactions include family stress among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Cogentin and Premarin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 13, 2026

53 people who take Cogentin and Premarin together, and have interactions are studied.

Cogentin and Premarin drug interactions.

What are the common drug interactions of Cogentin and Premarin, by gender? *:

female:

Family stress
Fibromyalgia (a long-term condition which causes pain all over the body)
Gallbladder disorder
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)
Gingival pain (gum pain)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Diarrhoea
Drug hypersensitivity

male:

Back pain
Blood pressure decreased
Syncope (loss of consciousness with an inability to maintain postural tone)
Granulocytopenia (lack of granulocyte)
Osteonecrosis (death of bone)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Crying
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Fall

What are the common drug interactions of Cogentin and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Abdominal discomfort
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Cough
Depression
Diabetes mellitus inadequate control
Diabetic foot
Drug abuse

40-49:

Type 2 diabetes mellitus
Blood pressure increased
Blood pressure systolic increased
Diarrhoea
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Haemoglobin decreased
Influenza
Malignant neoplasm progression (cancer tumour came back)
Metastases to liver (cancer spreads to liver)

50-59:

Chest pain
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depressed level of consciousness
Dysphagia (a condition in which swallowing is difficult or painful)
Dystonia (abnormal muscle tone)
Electrocardiogram qt prolonged
Erythema (redness of the skin)
Gallbladder disorder

60+:

Blood pressure decreased
Dyskinesia (abnormality or impairment of voluntary movement)
Blood culture positive
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusion
Crying
Culture urine positive
Deformity (disfigurement)
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 15.09%
Pain: 5 people, 9.43%
Stress And Anxiety: 4 people, 7.55%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 4 people, 7.55%
Bipolar Disorder (mood disorder): 4 people, 7.55%
Psychotic Disorder: 3 people, 5.66%
Panic Disorder: 3 people, 5.66%
High Blood Pressure: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and Premarin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously