Colace and Calan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colace (docusate ) and Calan (verapamil hydrochloride). Common drug interactions include chronic obstructive pulmonary disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Colace and Calan. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Calan?

Calan has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,916 Calan users. Check the latest studies of Calan.

On Jul, 06, 2026

47 people who take Colace and Calan together, and have interactions are studied.

What are the common drug interactions of Colace and Calan, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Vision blurred
Abdominal pain
Accident
Acute respiratory failure
Anaemia (lack of blood)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bipolar disorder (mood disorder)
Bleeding time prolonged

male:

Anxiety
Emotional distress
Abdominal pain
Cardiac arrest
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Neoplasm malignant (cancer tumour)
Pleural effusion (water on the lungs)
Skin swelling
Vomiting

What are the common drug interactions of Colace and Calan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sedation
Unevaluable reaction

30-39:

Aseptic necrosis bone
Electrocardiogram qt prolonged
Hypokalaemia (low potassium)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulsus bigeminus (groups of two heartbeats close together followed by a longer pause)
Ventricular extrasystoles (premature cardiac contraction)

40-49:

Anaemia (lack of blood)
Back pain
Bipolar disorder (mood disorder)
Candidiasis (candidiasis or thrush is a fungal infection)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Essential hypertension (primary hypertension)

50-59:

Vomiting
Abdominal pain
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anticoagulation drug level above therapeutic
Ascites (accumulation of fluid in the abdominal cavity)
Back pain
Blood creatinine increased
Blood pressure immeasurable
Cardiac arrest

60+:

Anxiety
Nausea (feeling of having an urge to vomit)
Vomiting
Accident
Anaemia (lack of blood)
Bleeding time prolonged
Blood fibrinogen decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Pain: 8 people, 17.02%
Nausea (feeling of having an urge to vomit): 8 people, 17.02%
Migraine (headache): 6 people, 12.77%
Sleep Disorder: 5 people, 10.64%
Dizziness: 5 people, 10.64%
Muscle Spasms (muscle contraction): 4 people, 8.51%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.51%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.38%
Itching: 3 people, 6.38%
Hypersensitivity: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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