Colace and Carpine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colace (docusate ) and Carpine (pilocarpine hydrochloride). Common drug interactions include dyspnoea among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Colace and Carpine. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Carpine?

Carpine has active ingredients of pilocarpine hydrochloride. eHealthMe is studying from 5,561 Carpine users. Check the latest studies of Carpine.

On Jul, 13, 2026

86 people who take Colace and Carpine together, and have interactions are studied.

What are the common drug interactions of Colace and Carpine, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Feeling drunk
Gastritis (inflammation of stomach)
Impaired gastric emptying
Limb injury
Loss of consciousness
Memory impairment
Migraine (headache)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vitamin d decreased

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Pain
Pain in extremity
Procedural site reaction
Pulmonary hypertension (increase in blood pressure in the lung artery)
Subcutaneous abscess
Subcutaneous haematoma (collection of blood outside the blood vessels on the skin)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Haemorrhage (bleeding)

What are the common drug interactions of Colace and Carpine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Cardiac disorder
Chest pain
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Injury
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Embolic stroke (stroke due to obstruction due to an embolus)
Pain
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fear

50-59:

Hallucination, visual (seeing things that aren't there)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoacusis (loss of hearing)
Immunodeficiency
Liver tenderness (pain and discomfort in liver when touched)
Malaise (a feeling of general discomfort or uneasiness)
Mouth haemorrhage (bleeding from mouth)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Cardiac arrest
Death
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diarrhoea
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fall

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 24.42%
Pain: 14 people, 16.28%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 15.12%
Multiple Myeloma (cancer of the plasma cells): 10 people, 11.63%
Immunodeficiency Common Variable: 10 people, 11.63%
Depression: 9 people, 10.47%
Dry Mouth: 7 people, 8.14%
Asthma: 7 people, 8.14%
Stress And Anxiety: 6 people, 6.98%
Muscle Spasms (muscle contraction): 6 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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