Colace and Ozempic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colace (docusate ) and Ozempic (semaglutide). Common drug interactions include cholelithiasis among females and ischaemic stroke among males.

The phase IV clinical study analyzes what interactions people have when they take Colace and Ozempic. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,762 Ozempic users. Check the latest studies of Ozempic.

On Aug, 11, 2026

74 people who take Colace and Ozempic together, and have interactions are studied.

What are the common drug interactions of Colace and Ozempic, by gender? *:

female:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Self esteem decreased (self worth reduced)
Abscess limb (limb infection)
Adenovirus infection
Adrenal neoplasm (abnormal growth of adrenal gland)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Ankle fracture
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthropathy

male:

Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Parkinson's disease
Spinal compression fracture (fracture due to spinal compression on bone)
Asthenia (weakness)
Disease progression
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pneumonia
Pseudarthrosis (bones that do not heal after fracture)

What are the common drug interactions of Colace and Ozempic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pancreatitis (inflammation of pancreas)

40-49:

Abdominal discomfort
Aggression
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthenia (weakness)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Ear infection
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

50-59:

Chronic kidney disease
Colon cancer
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Diarrhoea
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Fall
Flatulence (flatus expelled through the anus)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Blood pressure increased
Fall
Eye injury
Fatigue (feeling of tiredness)
Knee arthroplasty
Sinusitis (inflammation of sinus)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Death
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity

What are the existing conditions these people have? *

Type 2 Diabetes: 14 people, 18.92%
Diabetes: 12 people, 16.22%
Pain: 11 people, 14.86%
Immunodeficiency Common Variable: 10 people, 13.51%
High Blood Pressure: 9 people, 12.16%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 12.16%
Inflammatory Bowel Disease: 8 people, 10.81%
Diarrhea: 8 people, 10.81%
Gout (uric acid crystals building up in the body): 8 people, 10.81%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 10.81%

* Approximation only. Some reports may have incomplete information.

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