Colace and Rezulin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Colace (docusate ) and Rezulin (troglitazone). Common drug interactions include cough among females and osteomyelitis among males.
The phase IV clinical study analyzes what interactions people have when they take Colace and Rezulin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Colace?
Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.
What is Rezulin?
Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.
45 people who take Colace and Rezulin together, and have interactions are studied.

What are the common drug interactions of Colace and Rezulin, by gender? *:
female:
- Cough
- Anxiety
- Asthenia (weakness)
- Cellulitis (infection under the skin)
- Confusional state
- Fatigue (feeling of tiredness)
- Haematocrit decreased
- Haemoglobin decreased
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Red blood cell count decreased
male:
- Osteomyelitis (infection of bone)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Abscess (pus)
- Arteriosclerosis (thickening and hardening of arteries)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Blood creatinine increased
- Blood urea increased
What are the common drug interactions of Colace and Rezulin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Arrhythmia (irregular heartbeat)
- Cardiomyopathy (weakening of the heart muscle)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Osteomyelitis (infection of bone)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Echocardiogram abnormal
- Electrocardiogram abnormal
- Anxiety
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
40-49:
n/a
50-59:
- Fatigue (feeling of tiredness)
- Infection
- Melaena (the passage of black, tarry stools)
- Neck pain
- Obesity (having too much body fat)
- Pneumonia
- Skin ulcer
- Urinary tract infection
- Abscess (pus)
- Anaemia (lack of blood)
60+:
- Renal failure (kidney dysfunction)
- Haematocrit decreased
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Blood creatinine increased
- Cardiac failure congestive
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dyspnoea (difficult or laboured respiration)
- Pain
- Urinary tract infection
- Abscess (pus)
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 7 people, 15.56%
- Breast Cancer: 7 people, 15.56%
* Approximation only. Some reports may have incomplete information.
Do you take Colace and Rezulin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Colace and Rezulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rezulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rezulin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on docusate and troglitazone (the active ingredients of Colace and Rezulin, respectively), and Colace and Rezulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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