Colazal and Cymbalta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Colazal (balsalazide disodium) and Cymbalta (duloxetine hydrochloride). Common drug interactions include fall among females and cardiac failure among males.
The phase IV clinical study analyzes what interactions people have when they take Colazal and Cymbalta. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Colazal?
Colazal has active ingredients of balsalazide disodium. It is often used in ulcerative colitis. eHealthMe is studying from 1,232 Colazal users. Check the latest studies of Colazal.
What is Cymbalta?
Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.
17 people who take Colazal and Cymbalta together, and have interactions are studied.

What are the common drug interactions of Colazal and Cymbalta, by gender? *:
female:
- Fall
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Deafness
- Dizziness
- Escherichia infection (bacterial infection by escherichia coli)
- Hypersensitivity
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
- Red blood cell count decreased
- Restless legs syndrome (a powerful urge to move your legs)
male:
- Cardiac failure
- Dyspnoea (difficult or laboured respiration)
- Rash macular (small, flat red spots)
- Ulcer haemorrhage (bleeding ulcer)
- Haematemesis (vomiting of blood)
- Pneumonia
- Back injury
- Back pain
- Hypoaesthesia (reduced sense of touch or sensation)
- Nerve root compression
What are the common drug interactions of Colazal and Cymbalta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Fistula (an abnormal connection or passageway between two)
30-39:
n/a
40-49:
n/a
50-59:
- Contusion (a type of hematoma of tissue in which capillaries)
- Pruritus (severe itching of the skin)
- Rash macular (small, flat red spots)
60+:
- Cardiac failure
- Dyspnoea (difficult or laboured respiration)
- Drug ineffective
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Fall
- Fatigue (feeling of tiredness)
- Hepatic enzyme increased
- Nausea (feeling of having an urge to vomit)
- Panic disorder with agoraphobia (anxiety disorder in which a person has attacks of intense fear and anxiety)
- Ulcer haemorrhage (bleeding ulcer)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 8 people, 47.06%
- Dizziness: 8 people, 47.06%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 47.06%
- Nausea And Vomiting: 8 people, 47.06%
- Nausea (feeling of having an urge to vomit): 8 people, 47.06%
- Spinal Pain (pain in spine): 5 people, 29.41%
- Cardiac Disorder: 5 people, 29.41%
- Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 29.41%
- Urinary Tract Infection: 4 people, 23.53%
- Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 23.53%
* Approximation only. Some reports may have incomplete information.
Do you take Colazal and Cymbalta?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Colazal and Cymbalta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Colazal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cymbalta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colazal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cymbalta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on balsalazide disodium and duloxetine hydrochloride (the active ingredients of Colazal and Cymbalta, respectively), and Colazal and Cymbalta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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