Colchicine and Cabometyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colchicine (colchicine) and Cabometyx (cabozantinib s-malate). Common drug interactions include fall among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Colchicine and Cabometyx. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

What is Cabometyx?

Cabometyx has active ingredients of cabozantinib s-malate. eHealthMe is studying from 35,069 Cabometyx users. Check the latest studies of Cabometyx.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

68 people who take Colchicine and Cabometyx together, and have interactions are studied.

Colchicine and Cabometyx drug interactions.

What are the common drug interactions of Colchicine and Cabometyx, by gender? *:

female:

Fall
Full blood count decreased
Glomerular filtration rate decreased
Oral pain
Oropharyngeal pain
Peripheral swelling
Rash macular (small, flat red spots)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Epistaxis (bleed from the nose)
Headache (pain in head)

male:

Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Skin ulcer
Acne (skin problems that cause pimples)
Arthralgia (joint pain)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Circulatory collapse
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

What are the common drug interactions of Colchicine and Cabometyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Rash
Skin ulcer
Tongue disorder (disease of tongue)

50-59:

Gastritis (inflammation of stomach)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Heart rate increased
Oesophagitis (inflammation of oesophagus)

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Malignant neoplasm progression (cancer tumour came back)
Dysphonia (speech disorder attributable to a disorder of phonation)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Oral pain
Acne (skin problems that cause pimples)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Circulatory collapse
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 56 people, 82.35%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 7 people, 10.29%
High Blood Pressure: 7 people, 10.29%
Metastases To Bone (cancer spreads to bone): 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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