Colchicine and Gemcitabine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Colchicine (colchicine) and Gemcitabine (gemcitabine). Common drug interactions include nausea among females and bile duct stenosis among males.
The phase IV clinical study analyzes what interactions people have when they take Colchicine and Gemcitabine. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Colchicine?
Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.
What is Gemcitabine?
Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.
29 people who take Colchicine and Gemcitabine together, and have interactions are studied.

What are the common drug interactions of Colchicine and Gemcitabine, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Abdominal pain lower
- Abnormal faeces (abnormal stool)
- Anorectal discomfort
- Constipation
- Haematochezia (passage of stools containing blood)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Leukocytosis (increased white blood cells)
- Night sweats (sweating in night)
male:
- Bile duct stenosis (abnormal narrowing of the common bile duct)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Dyspnoea (difficult or laboured respiration)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Hypotension (abnormally low blood pressure)
- Oedema (fluid collection in tissue)
- Oedema peripheral (superficial swelling)
- Pyrexia (fever)
- Septic shock (shock due to blood infection)
- Swelling face
What are the common drug interactions of Colchicine and Gemcitabine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- Dyspnoea (difficult or laboured respiration)
- Pericardial effusion (fluid around the heart)
- Swelling face
30-39:
n/a
40-49:
n/a
50-59:
- Hypotension (abnormally low blood pressure)
- Septic shock (shock due to blood infection)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
- Cardiac tamponade (fluid accumulates in heart covering)
- Drug intolerance (drug sensitivity)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Leukopenia (less number of white blood cells in blood)
- Nausea (feeling of having an urge to vomit)
- Renal failure (kidney dysfunction)
- Thrombocytopenia (decrease of platelets in blood)
60+:
- Bile duct stenosis (abnormal narrowing of the common bile duct)
- Abdominal pain lower
- Night sweats (sweating in night)
- Oropharyngeal pain
- Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Vomiting
- Anaemia (lack of blood)
- Disease progression
- Myelosuppression (a decrease in the production of blood cells)
What are the existing conditions these people have? *
- Constipation: 8 people, 27.59%
- High Blood Pressure: 6 people, 20.69%
- Pain: 6 people, 20.69%
- Nausea (feeling of having an urge to vomit): 6 people, 20.69%
- Splenic Vein Thrombosis (blood clot in splenic vein): 4 people, 13.79%
- Nausea And Vomiting: 4 people, 13.79%
- Stress And Anxiety: 4 people, 13.79%
- Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 4 people, 13.79%
- Pancreatic Carcinoma (pancreatic cancer): 3 people, 10.34%
- Hepatocellular Carcinoma (liver cancer): 3 people, 10.34%
* Approximation only. Some reports may have incomplete information.
Do you take Colchicine and Gemcitabine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Colchicine (21,826 reports)
- Gemcitabine (31,337 reports)
Browse all drug interactions of Colchicine and Gemcitabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Colchicine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gemcitabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colchicine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemcitabine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .
- Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on colchicine and gemcitabine (the active ingredients of Colchicine and Gemcitabine, respectively), and Colchicine and Gemcitabine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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