Colchicine and Vimovo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colchicine (colchicine) and Vimovo (esomeprazole magnesium; naproxen). Common drug interactions include ankylosing spondylitis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colchicine and Vimovo. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

On Jul, 06, 2026

32 people who take Colchicine and Vimovo together, and have interactions are studied.

Colchicine and Vimovo drug interactions.

What are the common drug interactions of Colchicine and Vimovo, by gender? *:

female:

Ankylosing spondylitis (type of arthritis affecting the spine)
Chronic kidney disease
Renal failure (kidney dysfunction)
Ankle fracture
Arthralgia (joint pain)
Cartilage injury
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Drug ineffective
Fatigue (feeling of tiredness)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Acute myocardial infarction (acute heart attack)
Ankylosing spondylitis (type of arthritis affecting the spine)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fungal infection
Gastrointestinal inflammation (inflammation of stomach and intestine)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

What are the common drug interactions of Colchicine and Vimovo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ankylosing spondylitis (type of arthritis affecting the spine)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cerebral haemorrhage (bleeding within the brain)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Arthralgia (joint pain)
Cartilage injury
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Drug ineffective
Fatigue (feeling of tiredness)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Abdominal pain
Ankylosing spondylitis (type of arthritis affecting the spine)
Fatigue (feeling of tiredness)
Gastrointestinal inflammation (inflammation of stomach and intestine)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Iron deficiency
Muscle spasms (muscle contraction)

50-59:

Abdominal discomfort
Asthenia (weakness)
Fungal infection
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Pain in extremity
Sensory loss (senses loss)

60+:

Chronic kidney disease
Anaemia (lack of blood)
Renal disorder (kidney disease)
Renal injury (kidney injury)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Renal failure (kidney dysfunction)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Ankle fracture
Road traffic accident
Acute myocardial infarction (acute heart attack)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.00%
High Blood Pressure: 7 people, 21.88%
Indigestion: 6 people, 18.75%
Pain: 5 people, 15.62%
Anaemia (lack of blood): 4 people, 12.50%
Depression: 4 people, 12.50%
Constipation: 3 people, 9.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.38%
Hypersensitivity: 3 people, 9.38%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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