Colcrys and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colcrys (colchicine) and Azithromycin (azithromycin). Common drug interactions include chest pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colcrys and Azithromycin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Colcrys?

Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

45 people who take Colcrys and Azithromycin together, and have interactions are studied.

Colcrys and Azithromycin drug interactions.

What are the common drug interactions of Colcrys and Azithromycin, by gender? *:

female:

Chest pain
Ear pain
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Infusion related reaction
Infusion site pain
Infusion site scar
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Epicondylitis (tennis elbow)
Hypoaesthesia (reduced sense of touch or sensation)
Pain
Pneumonia
Skin cancer
Swelling
Wound
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Colcrys and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest pain
Dyspnoea (difficult or laboured respiration)
Ear pain
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Infusion related reaction
Infusion site pain
Infusion site scar
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)

30-39:

Osteonecrosis (death of bone)
Hip arthroplasty
Bone density decreased
Bone loss
Chronic kidney disease
Emotional distress
Gait disturbance
Knee arthroplasty
Mobility decreased (ability to move is reduced)
Multiple fractures

40-49:

Pneumonia
Renal failure (kidney dysfunction)
Rhinorrhoea (watery mucus discharge from the nose)
Sepsis (a severe blood infection that can lead to organ failure and death)
Staphylococcal infection (an infection with staphylococcus bacteria)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Wheezing (a high-pitched whistling sound made while you breath)
Blood pressure increased
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

50-59:

Renal failure (kidney dysfunction)
Chronic kidney disease
Abscess (pus)
Abscess neck (neck abscesses)
Anal abscess
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Cellulitis (infection under the skin)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Blood pressure increased
Carotid artery stenosis (narrowing of carotid artery)
Death
Emotional distress
Epicondylitis (tennis elbow)
Fall
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 28.89%
Immunodeficiency Common Variable: 13 people, 28.89%
Pain: 9 people, 20.00%
Infection: 8 people, 17.78%
High Blood Pressure: 8 people, 17.78%
Diabetes: 7 people, 15.56%
Cardiac Disorder: 6 people, 13.33%
Chest Pain: 6 people, 13.33%
Cough: 6 people, 13.33%
High Blood Cholesterol: 6 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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