Colcrys and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colcrys (colchicine) and Lidoderm (lidocaine). Common drug interactions include cyanosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colcrys and Lidoderm. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Colcrys?

Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

35 people who take Colcrys and Lidoderm together, and have interactions are studied.

What are the common drug interactions of Colcrys and Lidoderm, by gender? *:

female:

Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Abdominal distension
Fall
Nausea (feeling of having an urge to vomit)
Chronic kidney disease

male:

Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Hypoacusis (loss of hearing)
Nasopharyngitis (inflammation of the nasopharynx)
Nephropathy (damage to or disease of a kidney)
Red blood cell count decreased
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Vomiting
White blood cell count decreased

What are the common drug interactions of Colcrys and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cough
Diarrhoea
Dyspnoea (difficult or laboured respiration)

50-59:

Drug hypersensitivity
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Fall
Fear of disease
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Iron deficiency anaemia

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Facial bones fracture (bone fracture of face)
Fall
Gait disturbance
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Influenza
Pain in extremity
Red blood cell count decreased
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 25.71%
High Blood Cholesterol: 7 people, 20.00%
Constipation: 6 people, 17.14%
Diabetes: 6 people, 17.14%
Muscle Spasms (muscle contraction): 5 people, 14.29%
Stress And Anxiety: 5 people, 14.29%
Hyperkalemia (damage to or disease of the kidney): 5 people, 14.29%
Hypersensitivity: 5 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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