Colcrys and Robaxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Colcrys (colchicine) and Robaxin (methocarbamol). Common drug interactions include behcet's syndrome among females and international normalised ratio increased among males.
The phase IV clinical study analyzes what interactions people have when they take Colcrys and Robaxin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Colcrys?
Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.
What is Robaxin?
Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.
36 people who take Colcrys and Robaxin together, and have interactions are studied.

What are the common drug interactions of Colcrys and Robaxin, by gender? *:
female:
- Behcet's syndrome (involves inflammation of the blood vessels)
- Carbon dioxide increased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Decreased appetite
- Disturbance in attention
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Essential hypertension (primary hypertension)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Fungal infection
male:
- International normalised ratio increased
- Acute respiratory failure
- Dyspnoea exertional (breathlessness or shortness of breath)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Fluid overload (too much fluid in the blood)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hydronephrosis (water inside the kidney)
- Hyperglycaemia (high blood sugar)
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
- Hypertension (high blood pressure)
What are the common drug interactions of Colcrys and Robaxin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Abasia (inability to walk)
- Abdominal discomfort
- Anger
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Behcet's syndrome (involves inflammation of the blood vessels)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Disturbance in attention
- Drug ineffective
- Dyskinesia (abnormality or impairment of voluntary movement)
40-49:
- Tooth infection
- Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear)
- Eye pruritus (eye itching)
- Cellulitis (infection under the skin)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Fungal infection
- Pulmonary embolism (blockage of the main artery of the lung)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Staphylococcal infection (an infection with staphylococcus bacteria)
50-59:
- Anxiety
- Depression
- Drug hypersensitivity
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Nausea (feeling of having an urge to vomit)
- Pain
- Abdominal discomfort
- Abdominal distension
- Abdominal pain upper
- Alopecia (absence of hair from areas of the body)
60+:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Bladder spasm
- Carbon dioxide increased
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Constipation
- Cytomegalovirus infection
- Drug ineffective
- Dyspnoea exertional (breathlessness or shortness of breath)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
What are the existing conditions these people have? *
- Pain: 14 people, 38.89%
- Immunodeficiency Common Variable: 14 people, 38.89%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 19.44%
- Nausea (feeling of having an urge to vomit): 5 people, 13.89%
- Osteoporosis (bones weak and more likely to break): 4 people, 11.11%
- High Blood Pressure: 4 people, 11.11%
- Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 11.11%
- Renal Disorder (kidney disease): 3 people, 8.33%
- Neuralgia (pain in one or more nerves): 3 people, 8.33%
- Irritable Bowel Syndrome: 3 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Colcrys and Robaxin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Colcrys and Robaxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Colcrys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Robaxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colcrys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Robaxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on colchicine and methocarbamol (the active ingredients of Colcrys and Robaxin, respectively), and Colcrys and Robaxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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