Colcrys and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colcrys (colchicine) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colcrys and Valacyclovir. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Colcrys?

Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 09, 2026

82 people who take Colcrys and Valacyclovir together, and have interactions are studied.

Colcrys and Valacyclovir drug interactions.

What are the common drug interactions of Colcrys and Valacyclovir, by gender? *:

female:

Renal failure (kidney dysfunction)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Toothache (tooth pain)
Vomiting
Abdominal discomfort
Blood glucose increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Eye pruritus (eye itching)
Fall
Nephrogenic anaemia (anaemia due to kidney disease)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tooth loss
Arthropathy
Bone loss
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Hyperkalaemia (damage to or disease of the kidney)

What are the common drug interactions of Colcrys and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Osteonecrosis (death of bone)
Hip arthroplasty
Bone density decreased
Bone loss
Chronic kidney disease
Knee arthroplasty
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Renal failure (kidney dysfunction)
Rib fracture

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Bone density decreased
Chronic kidney disease
Drug ineffective
Emotional distress
Gait disturbance
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)

50-59:

Crest syndrome (thick, dry and fibrous skin)
Emotional distress
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Renal failure (kidney dysfunction)
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)

60+:

Blood pressure decreased
Platelet count decreased
Neoplasm malignant (cancer tumour)
Nephrolithiasis (calculi in the kidneys)
Peripheral swelling
Sinusitis (inflammation of sinus)
Skin wound
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Urinary tract infection
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 22 people, 26.83%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 25.61%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 21 people, 25.61%
Pain: 9 people, 10.98%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 9.76%
Hiv Infection: 7 people, 8.54%
High Blood Pressure: 6 people, 7.32%
Primary Immunodeficiency Syndrome: 5 people, 6.10%
High Blood Cholesterol: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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