Colestid and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colestid (colestipol hydrochloride) and Codeine (codeine sulfate). Common drug interactions include constipation among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Colestid and Codeine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Colestid?

Colestid has active ingredients of colestipol hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 2,233 Colestid users. Check the latest studies of Colestid.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.



On Jul, 22, 2026

16 people who take Colestid and Codeine together, and have interactions are studied.

Colestid and Codeine drug interactions.

What are the common drug interactions of Colestid and Codeine, by gender? *:

female:

  1. Constipation
  2. Joint swelling
  3. Rash
  4. Duodenal ulcer
  5. Humerus fracture (injury to the upper arm bone)
  6. Cyst (a closed sac)
  7. Drug specific antibody present
  8. Fibula fracture
  9. Infected cyst
  10. Ligament sprain (ligament stretched)

male:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Confusional state
  3. Cardiac arrest
  4. Hepatic failure (liver failure)
  5. Nephrolithiasis (calculi in the kidneys)
  6. Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)
  7. Septic shock (shock due to blood infection)
  8. Urinary retention postoperative

What are the common drug interactions of Colestid and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiac arrest
  2. Cyst (a closed sac)
  3. Drug hypersensitivity
  4. Hepatic failure (liver failure)
  5. Infected cyst
  6. Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)
  7. Septic shock (shock due to blood infection)

40-49:

n/a

50-59:

  1. Joint swelling
  2. Drug specific antibody present
  3. Fibula fracture
  4. Ligament sprain (ligament stretched)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Arthralgia (joint pain)
  7. Constipation

60+:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Confusional state
  3. Duodenal ulcer
  4. Humerus fracture (injury to the upper arm bone)
  5. Drug hypersensitivity
  6. Nephrolithiasis (calculi in the kidneys)
  7. Rash
  8. Urinary retention postoperative

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 10 people, 62.50%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 43.75%
  3. Stress And Anxiety: 6 people, 37.50%
  4. Diarrhea: 6 people, 37.50%
  5. Joint Pain: 6 people, 37.50%
  6. Hypokalemia (low potassium): 5 people, 31.25%
  7. Depression: 5 people, 31.25%
  8. Neuropathy Peripheral (surface nerve damage): 4 people, 25.00%
  9. Multiple Myeloma (cancer of the plasma cells): 4 people, 25.00%
  10. Fever: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Colestid and Codeine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Colestid and Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colestid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colestid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on colestipol hydrochloride and codeine sulfate (the active ingredients of Colestid and Codeine, respectively), and Colestid and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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