Combigan and Baclofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combigan (brimonidine tartrate; timolol maleate) and Baclofen (baclofen). Common drug interactions include surgery among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Combigan and Baclofen. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Combigan?

Combigan has active ingredients of brimonidine tartrate; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 7,810 Combigan users. Check the latest studies of Combigan.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

On Jul, 24, 2026

74 people who take Combigan and Baclofen together, and have interactions are studied.

Combigan and Baclofen drug interactions.

What are the common drug interactions of Combigan and Baclofen, by gender? *:

female:

Surgery
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Weight increased
Arthralgia (joint pain)
Gastric disorder (disease of stomach)
Interstitial lung disease
Liver disorder (liver diseases)
Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Thrombocytopenia (decrease of platelets in blood)

male:

Fatigue (feeling of tiredness)
Anxiety
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Upper respiratory tract infection
Drug ineffective
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Tooth disorder (tooth disease)
Cold sweat
Depression

What are the common drug interactions of Combigan and Baclofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Essential tremor
Nephrolithiasis (calculi in the kidneys)

30-39:

Vomiting

40-49:

Fall
Mobility decreased (ability to move is reduced)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Tooth disorder (tooth disease)
Depression
Fatigue (feeling of tiredness)
Interstitial lung disease
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain upper
Asthenia (weakness)

50-59:

Pneumonia
Thrombosis (formation of a blood clot inside a blood vessel)
Tremor (trembling or shaking movements in one or more parts of your body)
Trichorrhexis (a condition in which the hairs break)
Urinary tract infection
White blood cells urine positive
Blood cholesterol increased
Abdominal pain lower
Blood urine present
Bone pain

60+:

Upper respiratory tract infection
Back pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Colitis (inflammation of colon)
Drug ineffective
Hallucination (an experience involving the perception of something not present)
Hallucination, visual (seeing things that aren't there)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophagia (reduced food intake)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 22 people, 29.73%
Immunodeficiency Common Variable: 8 people, 10.81%
High Blood Pressure: 5 people, 6.76%
High Blood Cholesterol: 5 people, 6.76%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 6.76%
Diabetes: 5 people, 6.76%
Psychotic Disorder: 4 people, 5.41%
Multiple Myeloma (cancer of the plasma cells): 4 people, 5.41%
Immunodeficiency: 4 people, 5.41%
Delusion (a false belief or opinion): 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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