Combivent and Hydrea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivent (albuterol sulfate; ipratropium bromide) and Hydrea (hydroxyurea). Common drug interactions include dyspnoea among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Combivent and Hydrea. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.



On Jul, 10, 2026

18 people who take Combivent and Hydrea together, and have interactions are studied.

Combivent and Hydrea drug interactions.

What are the common drug interactions of Combivent and Hydrea, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Chest pain
  3. Haemoglobin decreased
  4. Headache (pain in head)
  5. Hospitalisation
  6. Influenza
  7. Nausea (feeling of having an urge to vomit)
  8. Pain
  9. Pain in extremity
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Abdominal pain
  3. Cough
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Depression
  7. Diarrhoea
  8. Drug abuser
  9. Drug dependence
  10. Drug ineffective

What are the common drug interactions of Combivent and Hydrea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Nausea (feeling of having an urge to vomit)
  4. Pain
  5. Vomiting
  6. Haemoglobin decreased
  7. Headache (pain in head)
  8. Hospitalisation
  9. Influenza
  10. Pain in extremity

50-59:

  1. Cerebral atrophy (decrement in size of brain)
  2. Cerebral disorder (brain disease)
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Renal impairment (severely reduced kidney function)
  6. White blood cell count decreased

60+:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Dyspnoea (difficult or laboured respiration)
  3. Gait disturbance
  4. Groin pain
  5. Haematoma (collection of blood outside the blood vessels)
  6. Insomnia (sleeplessness)
  7. International normalised ratio increased
  8. Lip oedema (swelling of lip)
  9. Platelet count increased
  10. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 33.33%
  2. Thrombocythaemia (an increased number of platelets in the circulating blood): 2 people, 11.11%
  3. Pain: 2 people, 11.11%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 11.11%
  5. Testicular Germ Cell Cancer (germ cell cancer of testes): 1 person, 5.56%
  6. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 5.56%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.56%
  8. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 5.56%
  9. Essential Thrombocythaemia (chronic blood cancer): 1 person, 5.56%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Combivent and Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and hydroxyurea (the active ingredients of Combivent and Hydrea, respectively), and Combivent and Hydrea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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