Combivent and Ofev drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combivent (albuterol sulfate; ipratropium bromide) and Ofev (nintedanib esylate). Common drug interactions include chest pain among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Combivent and Ofev. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Combivent?
Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.
What is Ofev?
Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
40 people who take Combivent and Ofev together, and have interactions are studied.

What are the common drug interactions of Combivent and Ofev, by gender? *:
female:
- Chest pain
- Decreased appetite
- Fall
- Hepatic enzyme increased
- Hypertension (high blood pressure)
- Infection
- Injury
- Limb injury
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Nephrolithiasis (calculi in the kidneys)
male:
- Diarrhoea
- Weight decreased
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Dyspepsia (indigestion)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Abdominal discomfort
- Abdominal distension
- Abdominal pain upper
- Anxiety
- Drug ineffective
What are the common drug interactions of Combivent and Ofev, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chest pain
- Herpes zoster
60+:
- Diarrhoea
- Nausea (feeling of having an urge to vomit)
- Flatulence (flatus expelled through the anus)
- Abdominal distension
- Asthenia (weakness)
- Vomiting
- Constipation
- Fall
- Abdominal pain
- Retching (strong involuntary effort to vomit)
What are the existing conditions these people have? *
- Idiopathic Pulmonary Fibrosis (chronic lung disease): 36 people, 90.00%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 15.00%
- High Blood Pressure: 5 people, 12.50%
- High Blood Cholesterol: 4 people, 10.00%
- Dyspnea (difficult or laboured breathing): 3 people, 7.50%
- Interstitial Lung Disease: 3 people, 7.50%
- Rickets (softening of bones): 3 people, 7.50%
- Chest Pain: 2 people, 5.00%
- Depression: 2 people, 5.00%
- Diabetic Ulcer: 2 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Combivent and Ofev?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Combivent and Ofev:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combivent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ofev:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ofev and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and nintedanib esylate (the active ingredients of Combivent and Ofev, respectively), and Combivent and Ofev (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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