Combivent and Yaz drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combivent (albuterol sulfate; ipratropium bromide) and Yaz (drospirenone; ethinyl estradiol). Common drug interactions include international normalised ratio decreased among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Combivent and Yaz. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Combivent?
Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.
What is Yaz?
Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.
78 people who take Combivent and Yaz together, and have interactions are studied.

What are the common drug interactions of Combivent and Yaz, by gender? *:
female:
- International normalised ratio decreased
- Memory impairment
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Mobility decreased (ability to move is reduced)
- Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
- Neutropenia (an abnormally low number of neutrophils)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pulmonary embolism (blockage of the main artery of the lung)
- Injury
- Pain
male:
- Pain
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Anxiety
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Fear
- Quality of life decreased
- Emotional distress
- Gait disturbance
- Hemiplegia (paralysis of one side of the body)
What are the common drug interactions of Combivent and Yaz, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Pain
- Anxiety
- Emotional distress
- Injury
- Chest pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gallbladder disorder
- Pulmonary embolism (blockage of the main artery of the lung)
- Pneumonia
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
20-29:
- Nausea (feeling of having an urge to vomit)
- Anxiety
- Depression
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Emotional distress
- Cholecystitis chronic (long lasting infection of gallbladder)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Vomiting
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
30-39:
- Flatulence (flatus expelled through the anus)
- General physical health deterioration (weak health status)
- Oedema peripheral (superficial swelling)
- Scar
- Gallbladder disorder
- Chest pain
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cough
- Gallbladder injury
- Hip fracture
40-49:
- Pulmonary embolism (blockage of the main artery of the lung)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Injury
- Pain
- Depression
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Pleuritic pain
- Productive cough
- Pulmonary congestion (congestion in the lungs)
50-59:
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
- Pain
- Fear
- Cough
- Abdominal pain
- Cholecystitis chronic (long lasting infection of gallbladder)
- Gallbladder disorder
- Anxiety
60+:
- Pain
- Gait disturbance
- Activities of daily living impaired
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
- Aphasia (damage to the parts of the brain that control language)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dysarthria (speech disorder)
What are the existing conditions these people have? *
- Premenstrual Syndrome: 25 people, 32.05%
- Acne (skin problems that cause pimples): 12 people, 15.38%
- Stress And Anxiety: 10 people, 12.82%
- Migraine (headache): 10 people, 12.82%
- Multiple Allergies (allergy to multiple agents): 7 people, 8.97%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 8.97%
- Pain: 6 people, 7.69%
- Menstruation Irregular: 6 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.69%
- Headache (pain in head): 5 people, 6.41%
* Approximation only. Some reports may have incomplete information.
Do you take Combivent and Yaz?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Combivent and Yaz:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combivent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Yaz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Yaz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and drospirenone; ethinyl estradiol (the active ingredients of Combivent and Yaz, respectively), and Combivent and Yaz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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