Combivir and Fentanyl drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Fentanyl (fentanyl citrate). Common drug interactions include somnolence among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Combivir and Fentanyl. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Combivir?
Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.
What is Fentanyl?
Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.
17 people who take Combivir and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Combivir and Fentanyl, by gender? *:
female:
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Breast hypoplasia (the post pubertal underdevelopment of a woman's breast tissue)
- Diarrhoea
- Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
- Finger deformity (a deformed position of the finger)
- Hospitalisation
- Hydrocephalus (water on the brain)
- Macrocephaly (a condition in which the head is larger than normal)
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Nail disorder (disease of nail)
male:
- Arthralgia (joint pain)
- Myalgia (muscle pain)
- Pulseless electrical activity
- Vomiting
- Agitation (state of anxiety or nervous excitement)
- Alanine aminotransferase increased
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Blood creatine phosphokinase increased
- Blood creatinine increased
- Coma (state of unconsciousness lasting more than six hours)
What are the common drug interactions of Combivir and Fentanyl, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthralgia (joint pain)
- Diarrhoea
- Hypersensitivity
- Influenza like illness
- Myalgia (muscle pain)
- Pyrexia (fever)
- Rhinorrhoea (watery mucus discharge from the nose)
- Viral infection
- Vomiting
- Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
40-49:
- Agitation (state of anxiety or nervous excitement)
- Drug ineffective
- Erythema multiforme (a type of hypersensitivity reaction)
- Headache (pain in head)
- Hyperpyrexia (extremely high fever)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Hypotension (abnormally low blood pressure)
- Kussmaul respiration (a deep and laboured breathing pattern)
- Multiple drug overdose
- Myalgia (muscle pain)
50-59:
- Pulseless electrical activity
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 3 people, 17.65%
- Quit Smoking: 1 person, 5.88%
- Normal Labor: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Combivir and Fentanyl?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Combivir and Fentanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fentanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fentanyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lamivudine; zidovudine and fentanyl citrate (the active ingredients of Combivir and Fentanyl, respectively), and Combivir and Fentanyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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