Combivir and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Vancomycin (vancomycin). Common drug interactions include rash among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Combivir and Vancomycin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.



On Jul, 09, 2026

34 people who take Combivir and Vancomycin together, and have interactions are studied.

Combivir and Vancomycin drug interactions.

What are the common drug interactions of Combivir and Vancomycin, by gender? *:

female:

  1. Rash
  2. Renal impairment (severely reduced kidney function)
  3. Renal tubular necrosis (death of kidney tubules)
  4. Sinusitis (inflammation of sinus)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Tooth injury
  7. Urinary tract infection
  8. Vision blurred
  9. Chronic kidney disease
  10. Renal failure (kidney dysfunction)

male:

  1. Emotional distress
  2. Pain
  3. Depression
  4. Renal impairment (severely reduced kidney function)
  5. Blood creatinine increased
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Tooth loss
  9. Death
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Combivir and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Death
  5. Decreased activity
  6. Emotional distress
  7. Fear
  8. Impaired work ability
  9. Pain
  10. Quality of life decreased

30-39:

  1. Renal cyst (kidney cyst)
  2. Renal injury (kidney injury)
  3. Renal tubular necrosis (death of kidney tubules)
  4. Bone loss
  5. Decreased activity
  6. Fatigue (feeling of tiredness)
  7. Hepatic enzyme increased
  8. Multiple fractures
  9. Multiple injuries
  10. Osteonecrosis (death of bone)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Renal failure (kidney dysfunction)
  7. Death
  8. Anaemia (lack of blood)
  9. Decreased activity
  10. Drooling (drop saliva uncontrollably from the mouth)

50-59:

  1. Emotional distress
  2. Pain
  3. Osteoporosis (bones weak and more likely to break)
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Bone density decreased
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Chronic kidney disease
  10. Renal failure (kidney dysfunction)

60+:

  1. Renal failure (kidney dysfunction)
  2. Anaemia (lack of blood)
  3. Hip fracture
  4. Insomnia (sleeplessness)
  5. Nephropathy (damage to or disease of a kidney)
  6. Osteonecrosis (death of bone)
  7. Osteoporosis (bones weak and more likely to break)
  8. Osteoporotic fracture (fracture due to weak bone)
  9. Pain
  10. Proteinuria (presence of protein in the urine)

What are the existing conditions these people have? *

  1. Hiv Infection: 34 people, 100.00%
  2. Pain: 4 people, 11.76%
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 11.76%
  4. Inflammation: 3 people, 8.82%
  5. High Blood Pressure: 3 people, 8.82%
  6. Hepatitis B: 3 people, 8.82%
  7. Bacterial Infection: 3 people, 8.82%
  8. Nausea (feeling of having an urge to vomit): 2 people, 5.88%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.88%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and Vancomycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Combivir and Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine and vancomycin (the active ingredients of Combivir and Vancomycin, respectively), and Combivir and Vancomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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