Compazine and Maxipime drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Compazine (prochlorperazine maleate) and Maxipime (cefepime hydrochloride). Common drug interactions include headache among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Compazine and Maxipime. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.
What is Compazine?
Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.
What is Maxipime?
Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.
77 people who take Compazine and Maxipime together, and have interactions are studied.

What are the common drug interactions of Compazine and Maxipime, by gender? *:
female:
- Headache (pain in head)
- Neutropenia (an abnormally low number of neutrophils)
- Pleural effusion (water on the lungs)
- Abscess limb (limb infection)
- Cellulitis (infection under the skin)
- Chest pain
- Cytomegalovirus viraemia (cytomegalo virus in blood stream)
- Dyspnoea (difficult or laboured respiration)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Infusion related reaction
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Bacteraemia (presence of bacteria in the blood)
- Platelet count decreased
- Chest pain
- Lymphocyte count decreased
- Asthenia (weakness)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Pneumonia
- Acute respiratory failure
- Anaemia (lack of blood)
What are the common drug interactions of Compazine and Maxipime, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Fatigue (feeling of tiredness)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Acute hepatic failure
- Arthralgia (joint pain)
- Aspartate aminotransferase increased
- Decreased appetite
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Epistaxis (bleed from the nose)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Headache (pain in head)
30-39:
- Asthenia (weakness)
- Chest discomfort
- Chest pain
- Cough
- Decreased appetite
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Headache (pain in head)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
40-49:
- Anaemia (lack of blood)
- Bacteraemia (presence of bacteria in the blood)
- Blood calcium increased
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Viral infection
- Chest pain
- Urinary tract infection
- Blood calcium decreased
50-59:
- Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Neutropenia (an abnormally low number of neutrophils)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pelvic abscess
- Platelet count decreased
- Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
- Rash
60+:
- Febrile neutropenia (fever with reduced white blood cells)
- White blood cell count decreased
- Lymphocyte count decreased
- Acute respiratory failure
- Pleural effusion (water on the lungs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Pancreatitis (inflammation of pancreas)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 35 people, 45.45%
- Pain: 25 people, 32.47%
- Constipation: 21 people, 27.27%
- Diarrhea: 20 people, 25.97%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 17 people, 22.08%
- Stress And Anxiety: 13 people, 16.88%
- Fever: 11 people, 14.29%
- Febrile Neutropenia (fever with reduced white blood cells): 11 people, 14.29%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 12.99%
- High Blood Pressure: 10 people, 12.99%
* Approximation only. Some reports may have incomplete information.
Do you take Compazine and Maxipime?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Compazine and Maxipime:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Maxipime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxipime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on prochlorperazine maleate and cefepime hydrochloride (the active ingredients of Compazine and Maxipime, respectively), and Compazine and Maxipime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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