Compazine and Viibryd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Compazine (prochlorperazine maleate) and Viibryd (vilazodone hydrochloride). Common drug interactions include diarrhoea among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Compazine and Viibryd. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Viibryd?

Viibryd has active ingredients of vilazodone hydrochloride. It is often used in depression. eHealthMe is studying from 11,106 Viibryd users. Check the latest studies of Viibryd.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

31 people who take Compazine and Viibryd together, and have interactions are studied.

Compazine and Viibryd drug interactions.

What are the common drug interactions of Compazine and Viibryd, by gender? *:

female:

Diarrhoea
Back pain
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Pain
Abdominal discomfort
Abdominal pain
Anaemia (lack of blood)
Bladder irritation
Constipation

male:

Haemoglobin decreased
Asthenia (weakness)
Panic attack
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Weight increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Decreased appetite
Dizziness

What are the common drug interactions of Compazine and Viibryd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Dizziness
Fatigue (feeling of tiredness)
Pain
Abdominal pain
Adrenomegaly (enlarged adrenal glands)
Anaemia (lack of blood)
Apnoea (suspension of external breathing)
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Bone pain

50-59:

Anaemia (lack of blood)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Ewing's sarcoma (malignant small, round, blue cell tumour)
Peripheral swelling

60+:

Abdominal discomfort
Bladder irritation
Joint injury
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Decreased appetite
Diarrhoea
Dry eye (lack of adequate tears)
Hysterectomy

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 25.81%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 8 people, 25.81%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 16.13%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.13%
Migraine (headache): 3 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 6.45%
Stress And Anxiety: 2 people, 6.45%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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