Compro and Ambien drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Compro (prochlorperazine) and Ambien (zolpidem tartrate). Common drug interactions include bone disorder among females and angiofibroma among males.
The phase IV clinical study analyzes what interactions people have when they take Compro and Ambien. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.
What is Compro?
Compro has active ingredients of prochlorperazine. eHealthMe is studying from 197 Compro users. Check the latest studies of Compro.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
49 people who take Compro and Ambien together, and have interactions are studied.

What are the common drug interactions of Compro and Ambien, by gender? *:
female:
- Bone disorder
- Cellulitis (infection under the skin)
- Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
- Eating disorder
- Emotional distress
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
- Exostosis (formation of new bone on the surface of a bone)
- Face injury
- Faecal incontinence (a lack of control over passing stool)
- Gingival pain (gum pain)
male:
- Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
- Anxiety
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cellulitis (infection under the skin)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Compression fracture (fracture due to pressure caused by injury)
- Contusion (a type of hematoma of tissue in which capillaries)
- Craniocerebral injury (injury to cranium and brain)
- Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
What are the common drug interactions of Compro and Ambien, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Pulmonary embolism (blockage of the main artery of the lung)
50-59:
- Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
- Anxiety
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
- Exostosis (formation of new bone on the surface of a bone)
- Face injury
- Faecal incontinence (a lack of control over passing stool)
- Gingival pain (gum pain)
- Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypoaesthesia (reduced sense of touch or sensation)
60+:
n/a
What are the existing conditions these people have? *
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 33 people, 67.35%
- Sleep Disorder: 22 people, 44.90%
- Depression: 20 people, 40.82%
- Nausea (feeling of having an urge to vomit): 19 people, 38.78%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 18 people, 36.73%
- Muscle Spasms (muscle contraction): 17 people, 34.69%
- Breast Cancer: 16 people, 32.65%
- Breast Cancer Metastatic: 15 people, 30.61%
- Migraine (headache): 3 people, 6.12%
- Drowsiness: 3 people, 6.12%
* Approximation only. Some reports may have incomplete information.
Do you take Compro and Ambien?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Compro and Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Compro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on prochlorperazine and zolpidem tartrate (the active ingredients of Compro and Ambien, respectively), and Compro and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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