Comtan and Temazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Comtan (entacapone) and Temazepam (temazepam). Common drug interactions include drug ineffective among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Comtan and Temazepam. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Comtan?

Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.

What is Temazepam?

Temazepam has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,106 Temazepam users. Check the latest studies of Temazepam.



On Jul, 10, 2026

18 people who take Comtan and Temazepam together, and have interactions are studied.

Comtan and Temazepam drug interactions.

What are the common drug interactions of Comtan and Temazepam, by gender? *:

female:

  1. Drug ineffective
  2. Decreased appetite
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Apnoea (suspension of external breathing)
  6. Asthenia (weakness)
  7. Chest pain
  8. Dizziness
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Anxiety
  2. Depression
  3. Nasal discharge discolouration (change in colour of nasal discharge)
  4. Suicidal ideation
  5. Back pain
  6. Death
  7. Dementia (madness)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Freezing phenomenon

What are the common drug interactions of Comtan and Temazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anxiety
  2. Depression
  3. Hypersexuality
  4. Pathological gambling
  5. Stress
  6. Back pain
  7. Compulsive shopping
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Freezing phenomenon

60+:

  1. Drug ineffective
  2. Dyspnoea (difficult or laboured respiration)
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Hepatic function abnormal
  6. Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
  7. Hyperventilation
  8. Hypotension (abnormally low blood pressure)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Memory impairment

What are the existing conditions these people have? *

  1. Depression: 5 people, 27.78%
  2. Pain: 2 people, 11.11%
  3. On And Off Phenomenon: 2 people, 11.11%
  4. High Blood Cholesterol: 2 people, 11.11%
  5. Erection Problems: 2 people, 11.11%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.11%
  7. Stress And Anxiety: 1 person, 5.56%
  8. Sleep Disorder: 1 person, 5.56%
  9. Joint Pain: 1 person, 5.56%
  10. Hypotension (abnormally low blood pressure): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Comtan and Temazepam?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Comtan and Temazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Comtan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Temazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Comtan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on entacapone and temazepam (the active ingredients of Comtan and Temazepam, respectively), and Comtan and Temazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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