Concerta and Clarithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Concerta (methylphenidate hydrochloride) and Clarithromycin (clarithromycin). Common drug interactions include migraine among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Concerta and Clarithromycin. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Concerta?

Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,041 Concerta users. Check the latest studies of Concerta.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 02, 2026

55 people who take Concerta and Clarithromycin together, and have interactions are studied.

Concerta and Clarithromycin drug interactions.

What are the common drug interactions of Concerta and Clarithromycin, by gender? *:

female:

Migraine (headache)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Stomatitis (inflammation of mucous membrane of mouth)
Surgery
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Upper respiratory tract infection
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pain
Vomiting

male:

Agitation (state of anxiety or nervous excitement)
Anxiety
Shoulder operation
Decreased appetite
Dysarthria (speech disorder)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Nasopharyngitis (inflammation of the nasopharynx)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Arthralgia (joint pain)

What are the common drug interactions of Concerta and Clarithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Nasopharyngitis (inflammation of the nasopharynx)
Lymphadenopathy (disease or enlargement of lymph nodes)
Meningitis streptococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Mouth ulceration (mouth ulcers)
Pain
Tonsillitis (inflammation of tonsil)
Vomiting
Arthralgia (joint pain)
Anaemia (lack of blood)

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Road traffic accident
Shoulder operation
Abdominal discomfort
Bronchial hyperreactivity
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Haemorrhagic ovarian cyst (bleeding ovarian cyst)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

30-39:

Anxiety
Balance disorder
Chest discomfort
Crying
Diarrhoea
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

40-49:

Drug ineffective

50-59:

Arthralgia (joint pain)
Limb injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Neck injury
Neck pain
Neuropathy peripheral (surface nerve damage)
Pain
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Road traffic accident
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

60+:

Herpes zoster

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 30 people, 54.55%
Immunodeficiency Common Variable: 5 people, 9.09%
Drowsiness: 5 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 7.27%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

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