Concerta and Lithobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Concerta (methylphenidate hydrochloride) and Lithobid (lithium carbonate). Common drug interactions include atrioventricular block complete among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Concerta and Lithobid. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Concerta?

Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,040 Concerta users. Check the latest studies of Concerta.

What is Lithobid?

Lithobid has active ingredients of lithium carbonate. It is often used in bipolar disorder. eHealthMe is studying from 1,281 Lithobid users. Check the latest studies of Lithobid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

15 people who take Concerta and Lithobid together, and have interactions are studied.

Concerta and Lithobid drug interactions.

What are the common drug interactions of Concerta and Lithobid, by gender? *:

female:

Atrioventricular block complete (heart block complete)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Hyperventilation
Loss of consciousness
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Panic reaction
Sick sinus syndrome (a collection of heart rhythm disorders)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abdominal distension
Alopecia (absence of hair from areas of the body)

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Suicidal ideation
Rash papular (redness with papule)
Rash pruritic (redness with itching)
Neuropathy peripheral (surface nerve damage)
Type 2 diabetes mellitus
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hyperglycaemia (high blood sugar)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Accident

What are the common drug interactions of Concerta and Lithobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Rash papular (redness with papule)
Rash pruritic (redness with itching)

10-19:

Accident
Alopecia (absence of hair from areas of the body)
Drug ineffective
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired healing

20-29:

Abdominal distension
Oedema peripheral (superficial swelling)
Weight increased

30-39:

n/a

40-49:

n/a

50-59:

Atrioventricular block complete (heart block complete)
Sick sinus syndrome (a collection of heart rhythm disorders)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Chest pain
Dizziness (excl vertigo)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gingival hyperplasia (overgrowth of gums)
Heart rate decreased
Nausea (feeling of having an urge to vomit)

60+:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Suicidal ideation
Neuropathy peripheral (surface nerve damage)
Type 2 diabetes mellitus

What are the existing conditions these people have? *

Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 4 people, 26.67%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 4 people, 26.67%
Stress And Anxiety: 2 people, 13.33%
Panic Disorder: 2 people, 13.33%
Hyperventilation: 2 people, 13.33%
Self Injurious Behavior: 1 person, 6.67%
Post-Traumatic Stress Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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