Concerta and Peppermint drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Concerta (methylphenidate hydrochloride) and Peppermint (peppermint). Common drug interactions include blood pressure increased among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Concerta and Peppermint. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Concerta?
Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,040 Concerta users. Check the latest studies of Concerta.
What is Peppermint?
Peppermint has active ingredients of peppermint. eHealthMe is studying from 1,327 Peppermint users. Check the latest studies of Peppermint.
14 people who take Concerta and Peppermint together, and have interactions are studied.

What are the common drug interactions of Concerta and Peppermint, by gender? *:
female:
- Blood pressure increased
- Alopecia (absence of hair from areas of the body)
- Application site erythema (redness of the skin at application site)
- Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
- Ear infection
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hypotension (abnormally low blood pressure)
- Labyrinthitis (inflammation of the labyrinth or inner ear)
- Nausea (feeling of having an urge to vomit)
male:
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Concerta and Peppermint, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
- Labyrinthitis (inflammation of the labyrinth or inner ear)
- Tympanic membrane perforation (a break in continuity of ear drum)
30-39:
- Administration site pain
- Application site erythema (redness of the skin at application site)
- Ear infection
- Sinusitis (inflammation of sinus)
- Skin infection
40-49:
n/a
50-59:
- Alopecia (absence of hair from areas of the body)
- Blood pressure increased
- Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
- Dizziness
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Joint swelling
- Oedema (fluid collection in tissue)
- Peripheral swelling
- Renal cyst (kidney cyst)
- Tinnitus (a ringing in the ears)
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 35.71%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 35.71%
- Immunodeficiency Common Variable: 4 people, 28.57%
- Dry Skin: 4 people, 28.57%
- Athlete's Foot (a fungal infection affecting the skin between the toes): 4 people, 28.57%
- Drowsiness: 2 people, 14.29%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
- Headache (pain in head): 1 person, 7.14%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Concerta and Peppermint?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Concerta (25,040 reports)
- Peppermint (1,327 reports)
Browse all drug interactions of Concerta and Peppermint:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Concerta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Peppermint:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Concerta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Peppermint and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride and peppermint (the active ingredients of Concerta and Peppermint, respectively), and Concerta and Peppermint (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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