Concerta and Se drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Concerta (methylphenidate hydrochloride) and Se (selenium). Common drug interactions include nausea among females and cognitive disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Concerta and Se. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Concerta?
Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,040 Concerta users. Check the latest studies of Concerta.
What is Se?
Se has active ingredients of selenium. eHealthMe is studying from 5,604 Se users. Check the latest studies of Se.
26 people who take Concerta and Se together, and have interactions are studied.

What are the common drug interactions of Concerta and Se, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Colitis ulcerative (inflammation of colon with ulcer)
- Diarrhoea
- Eating disorder
- Euphoric mood (excessively happy but may become angry or irritable)
- Eye pain
- Headache (pain in head)
male:
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Drug ineffective
- Rib fracture
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
- Sleep disorder
- Weight decreased
- Wheezing (a high-pitched whistling sound made while you breath)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspnoea (difficult or laboured respiration)
- Impaired work ability
What are the common drug interactions of Concerta and Se, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Keratomileusis
30-39:
- Nausea (feeling of having an urge to vomit)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Diarrhoea
- Eating disorder
- Eye pain
- Headache (pain in head)
- Insomnia (sleeplessness)
- Muscle twitching
- Pain
- Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
40-49:
n/a
50-59:
- Euphoric mood (excessively happy but may become angry or irritable)
- Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
- Mydriasis (a dilation of the pupil)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Tremor (trembling or shaking movements in one or more parts of your body)
60+:
- Fall
- Rib fracture
- Emotional disorder
- Glycosylated haemoglobin increased
- Insomnia (sleeplessness)
- Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Renal disorder (kidney disease)
- Sedation
- Syncope (loss of consciousness with an inability to maintain postural tone)
What are the existing conditions these people have? *
- Sleep Disorder: 19 people, 73.08%
- Stress And Anxiety: 7 people, 26.92%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 26.92%
- Type 2 Diabetes: 4 people, 15.38%
- Inflammation: 4 people, 15.38%
- Diabetic Foot: 4 people, 15.38%
- Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 4 people, 15.38%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
- Abdominal Pain Upper: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Concerta and Se?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Concerta and Se:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Concerta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Se:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Concerta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Se and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride and selenium (the active ingredients of Concerta and Se, respectively), and Concerta and Se (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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