Contrave and Multivitamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Contrave (bupropion hydrochloride; naltrexone hydrochloride) and Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include nausea among females and application site discolouration among males.

The phase IV clinical study analyzes what interactions people have when they take Contrave and Multivitamin. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Contrave?

Contrave has active ingredients of bupropion hydrochloride; naltrexone hydrochloride. It is often used in weight loss. eHealthMe is studying from 5,553 Contrave users. Check the latest studies of Contrave.

What is Multivitamin?

Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.

On Aug, 05, 2026

52 people who take Contrave and Multivitamin together, and have interactions are studied.

Contrave and Multivitamin drug interactions.

What are the common drug interactions of Contrave and Multivitamin, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Dizziness
Hot flush (sudden feelings of heat)
Constipation
Anxiety
Hypertension (high blood pressure)
Dyspnoea (difficult or laboured respiration)
Migraine (headache)
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Application site discolouration
Application site pain
Wound complication
Wound infection
Wound secretion
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Vomiting

What are the common drug interactions of Contrave and Multivitamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Palpitations (feelings or sensations that your heart is pounding or racing)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dizziness
Nausea (feeling of having an urge to vomit)
Abdominal distension
Anxiety
Disturbance in attention
Emotional disorder
Eye swelling
Headache (pain in head)

30-39:

Nausea (feeling of having an urge to vomit)
Panic attack
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Anxiety
Crying
Deafness
Dyspnoea (difficult or laboured respiration)
Emotional distress
Eye pain
Fatigue (feeling of tiredness)

40-49:

Nausea (feeling of having an urge to vomit)
Hot flush (sudden feelings of heat)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Dizziness
Anger
Anxiety
Blood pressure increased
Abdominal pain upper
Agitation (state of anxiety or nervous excitement)
Chest pain

50-59:

Migraine (headache)
Nausea (feeling of having an urge to vomit)
Constipation
Confusional state
Lethargy (tiredness)
Tremor (trembling or shaking movements in one or more parts of your body)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Drug hypersensitivity
Dry mouth
Tinnitus (a ringing in the ears)

60+:

Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Wound secretion
Drug administration error
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Heart rate increased
Immobile (not moving)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Depression

What are the existing conditions these people have? *

Weight Decreased: 21 people, 40.38%
High Blood Pressure: 7 people, 13.46%
Depression: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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