Copaxone and Ajovy drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Copaxone (glatiramer acetate) and Ajovy (fremanezumab-vfrm). Common drug interactions include injection site erythema among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Copaxone and Ajovy. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Copaxone?
Copaxone has active ingredients of glatiramer acetate. It is often used in multiple sclerosis. eHealthMe is studying from 56,931 Copaxone users. Check the latest studies of Copaxone.
What is Ajovy?
Ajovy has active ingredients of fremanezumab-vfrm. eHealthMe is studying from 8,834 Ajovy users. Check the latest studies of Ajovy.
12 people who take Copaxone and Ajovy together, and have interactions are studied.

What are the common drug interactions of Copaxone and Ajovy, by gender? *:
female:
- Injection site erythema (redness at injection site)
- Concussion (short loss of normal brain function in response to a head injury)
- Head injury
- Injection site bruising
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Weight increased
- Abdominal pain upper
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Arthralgia (joint pain)
- Blood iron decreased
male:
- Drug ineffective
What are the common drug interactions of Copaxone and Ajovy, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Injection site bruising
- Injection site erythema (redness at injection site)
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Abdominal pain upper
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Arthralgia (joint pain)
- Blood iron decreased
- Chest pain
- Eructation (release of gas from the digestive tract)
- Flatulence (flatus expelled through the anus)
60+:
- Injection site swelling
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Depression
- Disease progression
- Dystonia (abnormal muscle tone)
- Gait disturbance
- Hemiparesis (weakness on one side of the body)
- Hip arthroplasty
- Hospitalisation
- Hypertension (high blood pressure)
What are the existing conditions these people have? *
- Migraine (headache): 4 people, 33.33%
- Headache (pain in head): 2 people, 16.67%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 8.33%
- High Blood Pressure: 1 person, 8.33%
- Haemorrhage (bleeding): 1 person, 8.33%
- Bladder Disorder: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Copaxone and Ajovy?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Copaxone and Ajovy:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Copaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ajovy:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Copaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ajovy and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Michaud CJ, Bockheim HM, Nabeel M, Daum TE, "Diagnosis of Exclusion: A Case Report of Probable Glatiramer Acetate-Induced Eosinophilic Myocarditis", Case reports in neurological medicine, 2014 Jul .
- Michaud CJ, Bockheim HM, Nabeel M, Daum TE, "Diagnosis of Exclusion: A Case Report of Probable Glatiramer Acetate-Induced Eosinophilic Myocarditis", Case reports in neurological medicine, 2014 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on glatiramer acetate and fremanezumab-vfrm (the active ingredients of Copaxone and Ajovy, respectively), and Copaxone and Ajovy (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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