Copaxone and Restoril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Copaxone (glatiramer acetate) and Restoril (temazepam). Common drug interactions include chest pain among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Copaxone and Restoril. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.
What is Copaxone?
Copaxone has active ingredients of glatiramer acetate. It is often used in multiple sclerosis. eHealthMe is studying from 56,931 Copaxone users. Check the latest studies of Copaxone.
What is Restoril?
Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.
57 people who take Copaxone and Restoril together, and have interactions are studied.

What are the common drug interactions of Copaxone and Restoril, by gender? *:
female:
- Chest pain
- Depression
- Hypertension (high blood pressure)
- Nausea (feeling of having an urge to vomit)
- Abdominal pain upper
- Balance disorder
- Blindness
- Gait disturbance
- Headache (pain in head)
- Myalgia (muscle pain)
male:
- Dyspnoea (difficult or laboured respiration)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Actinic keratosis (skin disease due to sun exposure)
- Activities of daily living impaired
- Aggression
- Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arrhythmia (irregular heartbeat)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
What are the common drug interactions of Copaxone and Restoril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
10-19:
n/a
20-29:
- Arthralgia (joint pain)
- Chest discomfort
- Injection site reaction
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Dizziness
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Flushing (the warm, red condition of human skin)
- Injection site pain
30-39:
- Anxiety
- Asthenia (weakness)
- Ataxia (loss of full control of bodily movements)
- Pain
- Aphasia (damage to the parts of the brain that control language)
- Back pain
- Blood chloride increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Carbon dioxide decreased
- Chest pain
40-49:
- Back pain
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
- Cough
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Muscle stiffness
- Myalgia (muscle pain)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
50-59:
- Cerebral haematoma (collection of blood in brain)
- Cerebral haemorrhage (bleeding within the brain)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Confusional state
- Cranial nerve paralysis (loss of function of cranial nerve)
- Depression
- Device dislocation
- Diplopia (double vision)
- Eye pain
60+:
- Balance disorder
- Gait disturbance
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Nasopharyngitis (inflammation of the nasopharynx)
- Anxiety
- Bowel movement irregularity
- Cataract (clouding of the lens inside the eye)
- Chest pain
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 3 people, 5.26%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 5.26%
- Hypersensitivity: 3 people, 5.26%
- High Blood Pressure: 3 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Copaxone and Restoril?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Copaxone and Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Copaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Copaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restoril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Michaud CJ, Bockheim HM, Nabeel M, Daum TE, "Diagnosis of Exclusion: A Case Report of Probable Glatiramer Acetate-Induced Eosinophilic Myocarditis", Case reports in neurological medicine, 2014 Jul .
- Michaud CJ, Bockheim HM, Nabeel M, Daum TE, "Diagnosis of Exclusion: A Case Report of Probable Glatiramer Acetate-Induced Eosinophilic Myocarditis", Case reports in neurological medicine, 2014 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on glatiramer acetate and temazepam (the active ingredients of Copaxone and Restoril, respectively), and Copaxone and Restoril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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