Copegus and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Copegus (ribavirin) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include drug ineffective among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Copegus and Hydroxyzine. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

38 people who take Copegus and Hydroxyzine together, and have interactions are studied.

Copegus and Hydroxyzine drug interactions.

What are the common drug interactions of Copegus and Hydroxyzine, by gender? *:

female:

Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Feeling hot
Hypotension (abnormally low blood pressure)
Injection site erythema (redness at injection site)
Injection site reaction
International normalised ratio increased
Lip ulceration (ulcer of lip)
Memory impairment

male:

Rash
Loss of consciousness
Bone pain
Burning sensation
Cataract (clouding of the lens inside the eye)
Cold sweat
Confusional state
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Copegus and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dizziness
Drug hypersensitivity
Full blood count decreased
Infected skin ulcer
Infection
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Oral infection
Rash
Stomatitis (inflammation of mucous membrane of mouth)

50-59:

Bradycardia (abnormally slow heart action)
Pneumonia
Septic shock (shock due to blood infection)
Rash
Fluid overload (too much fluid in the blood)
Drug eruption (adverse drug reaction of the skin)
Leukaemia (blood or bone marrow cancer)
Panic attack
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

60+:

Anaemia (lack of blood)
Infection
Balance disorder
Blood sodium decreased
Chills (felling of cold)
Constipation
Diarrhoea
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dizziness
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Itching: 6 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.16%
Insomnia (sleeplessness): 4 people, 10.53%
Premenstrual Syndrome: 3 people, 7.89%
Pain: 3 people, 7.89%
Muscle Aches (muscle pain): 3 people, 7.89%
Dysthymia (mild chronic depression): 3 people, 7.89%
Drug Dependence: 3 people, 7.89%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 7.89%
Depression: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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