Copegus and Toprol-xl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Copegus (ribavirin) and Toprol-xl (metoprolol succinate). Common drug interactions include menstrual disorder among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Copegus and Toprol-xl. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

On Jul, 08, 2026

32 people who take Copegus and Toprol-xl together, and have interactions are studied.

Copegus and Toprol-xl drug interactions.

What are the common drug interactions of Copegus and Toprol-Xl, by gender? *:

female:

Menstrual disorder (disease of menstrual cycle)
Mood swings (an extreme or rapid change in mood)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Red blood cell sedimentation rate increased
Throat irritation
Tinea infection (fungal skin infection)
Tonsillitis (inflammation of tonsil)
Abdominal pain
Alanine aminotransferase increased
Aspartate aminotransferase increased

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neuropathy peripheral (surface nerve damage)
Fatigue (feeling of tiredness)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Skin discolouration (change of skin colour)
Vomiting
White blood cell count decreased
Acute respiratory failure
Alkalosis
Alopecia (absence of hair from areas of the body)

What are the common drug interactions of Copegus and Toprol-Xl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Blood calcium decreased
Dehydration (dryness resulting from the removal of water)
Heart rate increased
Infusion site reaction
Renal disorder (kidney disease)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Tooth abscess (pus formation in tooth)
Vision blurred
Weight fluctuation

40-49:

Dehydration (dryness resulting from the removal of water)
Depression
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
White blood cell count decreased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Blood potassium decreased
Blood thyroid stimulating hormone decreased

50-59:

Dry skin
Palpitations (feelings or sensations that your heart is pounding or racing)
Heart rate increased
Loss of consciousness
Pain
Neuropathy peripheral (surface nerve damage)
Alopecia (absence of hair from areas of the body)
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression

60+:

Anaemia (lack of blood)
Blood glucose increased
Skin discolouration (change of skin colour)
Cough
Hyperhidrosis (abnormally increased sweating)
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Tremor (trembling or shaking movements in one or more parts of your body)
White blood cell count decreased
Chest pain

What are the existing conditions these people have? *

Mood Swings (an extreme or rapid change in mood): 5 people, 15.62%
Depression: 5 people, 15.62%
Facial Pain: 3 people, 9.38%
Chest Pain: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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