Coq10 and Lomotil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coq10 (coenzyme q - 10) and Lomotil (atropine sulfate; diphenoxylate hydrochloride). Common drug interactions include pain in extremity among females and flatulence among males.
The phase IV clinical study analyzes what interactions people have when they take Coq10 and Lomotil. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Coq10?
Coq10 has active ingredients of coenzyme q - 10. It is often used in high blood cholesterol. eHealthMe is studying from 10,399 Coq10 users. Check the latest studies of Coq10.
What is Lomotil?
Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.
34 people who take Coq10 and Lomotil together, and have interactions are studied.

What are the common drug interactions of Coq10 and Lomotil, by gender? *:
female:
- Pain in extremity
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Infection
- Oedema peripheral (superficial swelling)
- White blood cell count decreased
- Asthenia (weakness)
male:
- Flatulence (flatus expelled through the anus)
- Pancreatic carcinoma (pancreatic cancer)
- Abdominal discomfort
- Abdominal distension
- Alopecia (absence of hair from areas of the body)
- Chronic lymphocytic leukaemia recurrent (repeated cancer of blood cells known as lymphocytes)
- Drug ineffective
- Dyspepsia (indigestion)
- Fall
- Haematochezia (passage of stools containing blood)
What are the common drug interactions of Coq10 and Lomotil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Gait disturbance
- Oedema peripheral (superficial swelling)
- Pain in extremity
50-59:
- Angiopathy (generic term for a disease of the blood vessels)
- Asthenia (weakness)
- Cholecystitis acute (rapid infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Dental caries
- Depression
- Haematocrit decreased
- Haemoglobin decreased
- Heart rate increased
60+:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Abdominal discomfort
- Abdominal pain
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Bone pain
- Catheter site infection (infection at the site of insertion)
- Culture positive
What are the existing conditions these people have? *
- Pain: 5 people, 14.71%
- Nausea (feeling of having an urge to vomit): 5 people, 14.71%
- High Blood Pressure: 5 people, 14.71%
- High Blood Cholesterol: 4 people, 11.76%
- Cardiac Disorder: 4 people, 11.76%
- Idiopathic Pulmonary Fibrosis (chronic lung disease): 4 people, 11.76%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.82%
- Thyroid Diseases: 3 people, 8.82%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
- Blood Uric Acid Increased: 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Coq10 and Lomotil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coq10 and Lomotil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coq10:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lomotil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coq10 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lomotil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on coenzyme q - 10 and atropine sulfate; diphenoxylate hydrochloride (the active ingredients of Coq10 and Lomotil, respectively), and Coq10 and Lomotil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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