Cordarone and Alendronate sodium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Alendronate sodium (alendronate sodium). Common drug interactions include overdose among females and electrocardiogram qt prolonged among males.
The phase IV clinical study analyzes what interactions people have when they take Cordarone and Alendronate sodium. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Cordarone?
Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.
What is Alendronate sodium?
Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.
19 people who take Cordarone and Alendronate sodium together, and have interactions are studied.

What are the common drug interactions of Cordarone and Alendronate Sodium, by gender? *:
female:
- Overdose
- Vision blurred
- Vomiting
- Weight decreased
- Blood thyroid stimulating hormone increased
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Gastrointestinal arteriovenous malformation (malformation of arteries and veins in gastrointestinal tract)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
male:
- Electrocardiogram qt prolonged
- Arthralgia (joint pain)
- Balance disorder
- Bedridden
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Breath sounds
- Cardiac failure congestive
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiomegaly (increased size of heart than normal)
- Cardiomyopathy (weakening of the heart muscle)
What are the common drug interactions of Cordarone and Alendronate Sodium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Electrocardiogram qt prolonged
- Cardioactive drug level increased
- Optic neuropathy (optic nerve damage)
- Overdose
- Vision blurred
- Vomiting
- Weight decreased
- Arthralgia (joint pain)
- Blood thyroid stimulating hormone increased
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.53%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 10.53%
- Cardiac Failure: 2 people, 10.53%
- Muscle Mass: 1 person, 5.26%
- High Blood Pressure: 1 person, 5.26%
- Constipation: 1 person, 5.26%
- Calcium Deficiency (lack of calcium): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Cordarone and Alendronate sodium?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cordarone (22,776 reports)
- Alendronate sodium (43,608 reports)
Browse all drug interactions of Cordarone and Alendronate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cordarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Alendronate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cordarone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alendronate sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on amiodarone hydrochloride and alendronate sodium (the active ingredients of Cordarone and Alendronate sodium, respectively), and Cordarone and Alendronate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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