Cordarone and Apresoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Apresoline (hydralazine hydrochloride). Common drug interactions include weight decreased among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Cordarone and Apresoline. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

On Jul, 15, 2026

23 people who take Cordarone and Apresoline together, and have interactions are studied.

Cordarone and Apresoline drug interactions.

What are the common drug interactions of Cordarone and Apresoline, by gender? *:

female:

Weight decreased
Abdominal pain
Cardiac failure acute
Cardiac failure chronic
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Left ventricular failure (left ventricle fails to contract forcefully)
Back pain
Blood pressure decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)

male:

Cardiac failure congestive
Pneumonia
Fungal infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pain
Respiratory distress (difficulty in breathing)
Troponin increased
Abdominal pain

What are the common drug interactions of Cordarone and Apresoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Insomnia (sleeplessness)
Blood creatine phosphokinase increased
Blood potassium decreased
Cardiac disorder
Cardiac failure congestive
Chest pain

50-59:

Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic anaemia (anaemia due to excessive bleeding)

60+:

Cardiac failure congestive
Pneumonia
Atelectasis (partial or complete collapse of the lung)
Blood creatinine increased
Chest pain
Coagulopathy (blood's ability to clot is impaired)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid overload (too much fluid in the blood)
Fungal infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

Pain: 5 people, 21.74%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 17.39%
Muscle Spasms (muscle contraction): 3 people, 13.04%
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 3 people, 13.04%
Constipation: 3 people, 13.04%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.70%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.70%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Dyspnea (difficult or laboured breathing): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Cordarone and Apresoline?

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