Cordarone and Avelox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Avelox (moxifloxacin hydrochloride). Common drug interactions include alopecia among females and syncope among males.
The phase IV clinical study analyzes what interactions people have when they take Cordarone and Avelox. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Cordarone?
Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.
What is Avelox?
Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.
51 people who take Cordarone and Avelox together, and have interactions are studied.

What are the common drug interactions of Cordarone and Avelox, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Atrioventricular block (heart block)
- Back pain
- Balance disorder
- Blood glucose increased
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cardiomegaly (increased size of heart than normal)
- Carotid artery aneurysm (a bulging or ballooning in the wall of a blood vessel)
- Cellulitis (infection under the skin)
- Chest pain
male:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Hypotension (abnormally low blood pressure)
- Haematoma (collection of blood outside the blood vessels)
- Hypertension (high blood pressure)
- Oedema peripheral (superficial swelling)
- Pain
- Renal failure chronic (long lasting kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Chest pain
What are the common drug interactions of Cordarone and Avelox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Gastric haemorrhage (bleeding stomach)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- Cardiac arrest
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram qt prolonged
- Loss of consciousness
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
- Ventricular fibrillation (abnormally irregular heart rhythm)
50-59:
n/a
60+:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Cardiac failure congestive
- Chest pain
- Hypertension (high blood pressure)
- Multiple injuries
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Haematoma (collection of blood outside the blood vessels)
- Oedema peripheral (superficial swelling)
- Renal failure acute (rapid kidney dysfunction)
What are the existing conditions these people have? *
- Pneumonia: 3 people, 5.88%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Cordarone and Avelox?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cordarone and Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cordarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cordarone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avelox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on amiodarone hydrochloride and moxifloxacin hydrochloride (the active ingredients of Cordarone and Avelox, respectively), and Cordarone and Avelox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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