Cordarone and Luvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Luvox (fluvoxamine maleate). Common drug interactions include disorientation among females and rib fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Cordarone and Luvox. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

What is Luvox?

Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,440 Luvox users. Check the latest studies of Luvox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

17 people who take Cordarone and Luvox together, and have interactions are studied.

What are the common drug interactions of Cordarone and Luvox, by gender? *:

female:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination (an experience involving the perception of something not present)
International normalised ratio increased
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Prothrombin time ratio decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Glomerulonephritis chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli)
Hepatitis toxic
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Platelet count decreased

male:

Rib fracture
Confusional state
Fall
Gamma-glutamyltransferase increased
Head injury
Insomnia (sleeplessness)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fatigue (feeling of tiredness)
Pathological fracture (broken bone caused by disease)

What are the common drug interactions of Cordarone and Luvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Confusional state
Prothrombin time ratio decreased
Ascites chylous (presence of a milky & creamy ascetic fluid with a triglyceride in the abdominal cavity)
Asthenia (weakness)
Blood alkaline phosphatase nos increased
Gamma-glutamyltransferase increased
Insomnia (sleeplessness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sweating increased (excess sweating)

What are the existing conditions these people have? *

Depression: 3 people, 17.65%
Peripheral Ischaemia (impaired circulation to an extremity): 2 people, 11.76%
Ill-Defined Disorder: 2 people, 11.76%
Psychosomatic Disease (situation in which the mind influences the body to create or complicate an illness): 1 person, 5.88%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Hyperthyroidism (over activity of the thyroid gland): 1 person, 5.88%
Enlarged Prostate: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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