Corgard and Norco drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Corgard (nadolol) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include coronary artery disease among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Corgard and Norco. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Corgard?
Corgard has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 3,342 Corgard users. Check the latest studies of Corgard.
What is Norco?
Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.
45 people who take Corgard and Norco together, and have interactions are studied.

What are the common drug interactions of Corgard and Norco, by gender? *:
female:
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Coronary artery stenosis (narrowing of coronary artery)
- Costochondritis (chest wall pain)
- Cough
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic autonomic neuropathy (diabetes with nerve disorder, painful muscle wasting and weakness)
- Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
- Diarrhoea
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Drug ineffective
male:
- Asthenia (weakness)
- Diarrhoea
- Weight fluctuation
- Small intestinal obstruction (blockage in small intestine)
- Malaise (a feeling of general discomfort or uneasiness)
- Activities of daily living impaired
- Anal abscess
- Chronic kidney disease
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Corgard and Norco, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abortion induced (medically referred abortion)
- Anxiety
- Deafness
- Depression
- Disturbance in attention
- Facial pain
- Headache (pain in head)
- Injury
- Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
- Jugular vein thrombosis (clot in jugular vein)
30-39:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Gallbladder disorder
- Pulmonary embolism (blockage of the main artery of the lung)
40-49:
- Body temperature increased
- Completed suicide (act of taking one's own life)
- Depression
- Ear discomfort
- Ear pain
- Overdose
- Pruritus (severe itching of the skin)
- Suicidal ideation
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Dizziness
50-59:
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Hypotension (abnormally low blood pressure)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Hypoxia (low oxygen in tissues)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Hysterectomy
- Ill-defined disorder
- Injury
- Insomnia (sleeplessness)
60+:
- Asthenia (weakness)
- Diarrhoea
- Dry throat
- Arthralgia (joint pain)
- Chest discomfort
- Chest pain
- Chronic kidney disease
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 11 people, 24.44%
- Migraine (headache): 11 people, 24.44%
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 11 people, 24.44%
- Headache (pain in head): 9 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 20.00%
- High Blood Cholesterol: 6 people, 13.33%
- Stress And Anxiety: 6 people, 13.33%
- Neuropathy Peripheral (surface nerve damage): 6 people, 13.33%
- Nausea (feeling of having an urge to vomit): 5 people, 11.11%
- Gastric Ulcer (stomach ulcer): 4 people, 8.89%
* Approximation only. Some reports may have incomplete information.
Do you take Corgard and Norco?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Corgard and Norco:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Corgard:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Norco:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Corgard and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Norco and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nadolol and acetaminophen; hydrocodone bitartrate (the active ingredients of Corgard and Norco, respectively), and Corgard and Norco (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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