Corgard and Pegasys drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Corgard (nadolol) and Pegasys (peginterferon alfa 2a). Common drug interactions include arterial stenosis among females and thrombocytopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Corgard and Pegasys. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Corgard?
Corgard has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 3,342 Corgard users. Check the latest studies of Corgard.
What is Pegasys?
Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.
16 people who take Corgard and Pegasys together, and have interactions are studied.

What are the common drug interactions of Corgard and Pegasys, by gender? *:
female:
- Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
- Peripheral ischaemia (impaired circulation to an extremity)
- Hepatocellular injury (liver injury)
- Liver transplant
- Transplant rejection (a transplant material is not worked)
- Urinary tract infection
- Anaemia (lack of blood)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Drug eruption (adverse drug reaction of the skin)
- Eosinophil count increased
male:
- Thrombocytopenia (decrease of platelets in blood)
- Anaemia (lack of blood)
- Hepatic lesion
- Hepatic neoplasm (liver tumour)
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Abdominal distension
- Abdominal rigidity
- Blood glucose decreased
- Chest pain
What are the common drug interactions of Corgard and Pegasys, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dyspnoea (difficult or laboured respiration)
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Lung disorder (lung disease)
- Vomiting
50-59:
- Depression
- Drug ineffective
- Gallbladder disorder
- Nausea (feeling of having an urge to vomit)
- Pancreatic disorder
- Thrombocytopenia (decrease of platelets in blood)
- Hepatocellular injury (liver injury)
- Liver transplant
- Transplant rejection (a transplant material is not worked)
- Urinary tract infection
60+:
- Anaemia (lack of blood)
- Hepatic neoplasm malignant (liver cancer)
- Thrombocytopenia (decrease of platelets in blood)
- Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
- Hepatic lesion
- Hepatic neoplasm (liver tumour)
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
What are the existing conditions these people have? *
- Varices Oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach): 1 person, 6.25%
- Rashes (redness): 1 person, 6.25%
- Mitral Valve Prolapse (heart's mitral valve doesn't work well): 1 person, 6.25%
- Hepatitis B: 1 person, 6.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
- Back Pain: 1 person, 6.25%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Corgard and Pegasys?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Corgard and Pegasys:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Corgard:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pegasys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Corgard and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pegasys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nadolol and peginterferon alfa 2a (the active ingredients of Corgard and Pegasys, respectively), and Corgard and Pegasys (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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